Recent News

Upcoming Events

22
Oct

Workshop:<br><b>Perception-Thought Transitions</b>

October 22
8:00 am - 5:00 pm
22
Oct

<i>Psychology</i> <br>Michael Levin (Tufts University) <br><b>How Cognition Emerges in Cell Collectives</b>

October 22
3:00 pm - 4:30 pm
12
Nov

<i>Psychology</i> <br>Justin Wood (Indiana University Bloomington) <br><b>Origins of Intelligence in Animals and Machines</b>

November 12
2:00 pm - 3:30 pm

Relevant Publications

For full list of selected publications, see the publications page

Extinction context is learned by pigeons, not given by the environment

18825267 {18825267:9N73ZRPX} 1 apa 50 default 6053 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%229N73ZRPX%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Peschken%20et%20al.%22%2C%22parsedDate%22%3A%222025-05-24%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPeschken%2C%20J.%2C%20Hahn%2C%20L.%20A.%2C%20Pusch%2C%20R.%2C%20%26amp%3B%20Rose%2C%20J.%20%282025%29.%20Extinction%20context%20is%20learned%20by%20pigeons%2C%20not%20given%20by%20the%20environment.%20%26lt%3Bi%26gt%3BCommunications%20Psychology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B3%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%2083.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs44271-025-00261-2%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs44271-025-00261-2%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Extinction%20context%20is%20learned%20by%20pigeons%2C%20not%20given%20by%20the%20environment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juan%22%2C%22lastName%22%3A%22Peschken%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lukas%20Alexander%22%2C%22lastName%22%3A%22Hahn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pusch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%22%2C%22lastName%22%3A%22Rose%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20The%20saying%20%5Cu201ccontext%20is%20everything%5Cu201d%20underscores%20the%20importance%20of%20interpreting%20things%2C%20be%20they%20quotes%2C%20events%2C%20actions%2C%20or%20stimuli%2C%20not%20in%20isolation%20but%20in%20the%20light%20of%20a%20bigger%20picture%20-%20their%20context.%20This%20is%20evident%20even%20in%20fundamental%20forms%20of%20learning%20such%20as%20extinction%20learning%20where%2C%20in%20contextual%20renewal%2C%20an%20extinguished%20response%20reoccurs%20if%20the%20context%20is%20changed.%20But%20what%20exactly%20is%20context%3F%20Is%20context%20given%20by%20stimuli%20with%20inherent%20properties%20making%20them%20context%20or%2C%20what%20are%20the%20circumstances%20that%20allow%20a%20stimulus%20to%20become%20%5Cu201ccontextual%5Cu201d%3F%20Even%20though%20the%20answer%20may%20seem%20intuitively%20trivial%2C%20the%20literature%20only%20provides%20competing%20and%20vague%20definitions.%20Using%20a%20modified%20ABA%20paradigm%2C%20we%20assessed%20how%20competing%20stimuli%20induced%20contextual%20renewal%20during%20extinction%20learning%20in%20seven%20pigeons%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Columba%20livia%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20Furthermore%2C%20we%20controlled%20the%20timing%20of%20these%20stimuli%20and%20found%20it%20to%20be%20crucial%3B%20with%20the%20right%20contiguity%2C%20even%20small%20local%20stimuli%20resulted%20in%20the%20strongest%20contextual%20renewal.%20This%20result%20challenges%20definitions%20of%20context%20as%20%5Cu2018a%20backdrop%20where%20learning%20occurs%5Cu2019.%20Instead%2C%20we%20propose%20that%20context%20can%20be%20understood%20mechanistically%20as%20a%20learned%20stimulus%20property.%20Therefore%2C%20context%20truly%20is%20everything%20and%20anything.%22%2C%22date%22%3A%222025-05-24%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs44271-025-00261-2%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs44271-025-00261-2%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%222731-9121%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A05Z%22%7D%7D%5D%7D
Peschken, J., Hahn, L. A., Pusch, R., & Rose, J. (2025). Extinction context is learned by pigeons, not given by the environment. Communications Psychology, 3(1), 83. https://doi.org/10.1038/s44271-025-00261-2

Movie-watching evokes ripple-like activity within events and at event boundaries

18825267 {18825267:MNHITNJ8} 1 apa 50 default 6049 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22MNHITNJ8%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Silva%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSilva%2C%20M.%2C%20Wu%2C%20X.%2C%20Sabio%2C%20M.%2C%20Conde-Blanco%2C%20E.%2C%20Rold%26%23xE1%3Bn%2C%20P.%2C%20Donaire%2C%20A.%2C%20Carre%26%23xF1%3Bo%2C%20M.%2C%20Axmacher%2C%20N.%2C%20Baldassano%2C%20C.%2C%20%26amp%3B%20Fuentemilla%2C%20L.%20%282025%29.%20Movie-watching%20evokes%20ripple-like%20activity%20within%20events%20and%20at%20event%20boundaries.%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B16%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%205647.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-025-60788-0%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-025-60788-0%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Movie-watching%20evokes%20ripple-like%20activity%20within%20events%20and%20at%20event%20boundaries%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marta%22%2C%22lastName%22%3A%22Silva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xiongbo%22%2C%22lastName%22%3A%22Wu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marc%22%2C%22lastName%22%3A%22Sabio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Estefan%5Cu00eda%22%2C%22lastName%22%3A%22Conde-Blanco%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pedro%22%2C%22lastName%22%3A%22Rold%5Cu00e1n%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antonio%22%2C%22lastName%22%3A%22Donaire%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mar%22%2C%22lastName%22%3A%22Carre%5Cu00f1o%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nikolai%22%2C%22lastName%22%3A%22Axmacher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christopher%22%2C%22lastName%22%3A%22Baldassano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Llu%5Cu00eds%22%2C%22lastName%22%3A%22Fuentemilla%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025-07-01%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-025-60788-0%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41467-025-60788-0%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%222041-1723%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A08Z%22%7D%7D%5D%7D
Silva, M., Wu, X., Sabio, M., Conde-Blanco, E., Roldán, P., Donaire, A., Carreño, M., Axmacher, N., Baldassano, C., & Fuentemilla, L. (2025). Movie-watching evokes ripple-like activity within events and at event boundaries. Nature Communications, 16(1), 5647. https://doi.org/10.1038/s41467-025-60788-0

Regional prefrontal and hippocampal differences in gray matter volume are linked to the propensity for renewal in extinction learning

18825267 {18825267:IKXUVIP3} 1 apa 50 default 6045 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22IKXUVIP3%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Lissek%20and%20Tegenthoff%22%2C%22parsedDate%22%3A%222025-07-03%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLissek%2C%20S.%2C%20%26amp%3B%20Tegenthoff%2C%20M.%20%282025%29.%20Regional%20prefrontal%20and%20hippocampal%20differences%20in%20gray%20matter%20volume%20are%20linked%20to%20the%20propensity%20for%20renewal%20in%20extinction%20learning.%20%26lt%3Bi%26gt%3BFrontiers%20in%20Behavioral%20Neuroscience%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B19%26lt%3B%5C%2Fi%26gt%3B%2C%201592929.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffnbeh.2025.1592929%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffnbeh.2025.1592929%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Regional%20prefrontal%20and%20hippocampal%20differences%20in%20gray%20matter%20volume%20are%20linked%20to%20the%20propensity%20for%20renewal%20in%20extinction%20learning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silke%22%2C%22lastName%22%3A%22Lissek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Tegenthoff%22%7D%5D%2C%22abstractNote%22%3A%22Introduction%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20The%20renewal%20effect%20of%20extinction%20describes%20the%20reoccurrence%20of%20an%20extinguished%20response%20if%20recall%20is%20performed%20in%20a%20context%20that%20is%20not%20the%20same%20as%20the%20extinction%20context.%20This%20learning%20phenomenon%20is%20clinically%20relevant%2C%20since%20it%20potentially%20interferes%20with%20therapy%20success%20for%20anxiety%20disorders%20or%20phobias.%20The%20propensity%20to%20show%20the%20renewal%20effect%20appears%20to%20be%20a%20stable%20processing%20strategy%20in%20context-related%20extinction%2C%20associated%20with%20higher%20BOLD%20activation%20in%20hippocampus%2C%20ventromedial%20PFC%20%28vmPFC%29%20and%20inferior%20frontal%20gyrus%20%28IFG%29%20in%20individuals%20who%20show%20renewal%20%28REN%29%20compared%20to%20those%20who%20do%20not%20%28NoREN%29.%20However%2C%20evidence%20on%20a%20potential%20relationship%20between%20structural%20properties%20such%20as%20gray%20matter%20volume%20%28GMV%29%20in%20these%20regions%20and%20the%20propensity%20to%20show%20renewal%20is%20lacking.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Methods%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20In%20this%20study%2C%20we%20applied%20voxel-based%20morphometry%20%28VBM%29%20to%20investigate%20whether%20individuals%20with%20and%20without%20a%20propensity%20for%20renewal%20differ%20regarding%20their%20GMV%20in%20extinction-related%20brain%20regions%2C%20and%20whether%20such%20a%20difference%20is%20linked%20to%20the%20renewal%20level.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Results%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Results%20revealed%20differential%20GMV%20in%20REN%20and%20NoREN%20in%20adjacent%20subregions%20of%20IFG%20and%20vmPFC%2C%20respectively.%20Higher%20GMV%20in%20REN%20was%20located%20predominantly%20in%20orbital%20IFG%20and%20in%20BA10%20of%20vmPFC.%20Higher%20GMV%20in%20NoREN%20was%20located%20predominantly%20in%20triangular%20IFG%20and%20in%20BA%2011%20of%20vmPFC.%20In%20bilateral%20anterior%20cingulate%20cortex%20%28ACC%29%20and%20anterior%20hippocampus%2C%20GMV%20was%20overall%20higher%20in%20NoREN.%20In%20the%20complete%20sample%2C%20higher%20GMV%20in%20IFG%20BA%2047%2C%20vmPFC%20BA11%2C%20bilateral%20ACC%20and%20bilateral%20anterior%20hippocampus%20was%20associated%20with%20less%20renewal%2C%20and%20partially%20with%20a%20higher%20error%20level%20in%20extinction%20learning%20in%20a%20novel%20context.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Discussion%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20The%20findings%20suggest%20that%20higher%20GMV%20in%20several%20regions%20active%20during%20extinction%20learning%20may%20support%20a%20more%20thorough%20processing%20of%20extinction%20trials%20which%20in%20turn%20could%20be%20conducive%20to%20an%20extinction%20recall%20solely%20based%20on%20recent%20extinction%20memory%2C%20disregarding%20context%20information.%20In%20summary%2C%20this%20study%20provides%20first-time%20evidence%20for%20a%20relationship%20of%20GMV%20in%20of%20extinction-%20and%20renewal-relevant%20brain%20regions%20with%20behavioral%20performance%20during%20extinction%20learning%20and%20the%20propensity%20to%20show%20the%20renewal%20effect.%22%2C%22date%22%3A%222025-7-3%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.3389%5C%2Ffnbeh.2025.1592929%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.frontiersin.org%5C%2Farticles%5C%2F10.3389%5C%2Ffnbeh.2025.1592929%5C%2Ffull%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221662-5153%22%2C%22language%22%3A%22%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Lissek, S., & Tegenthoff, M. (2025). Regional prefrontal and hippocampal differences in gray matter volume are linked to the propensity for renewal in extinction learning. Frontiers in Behavioral Neuroscience, 19, 1592929. https://doi.org/10.3389/fnbeh.2025.1592929

Reference in memories from perceptual and non-perceptual experiences: a non-disjunctivist account including vicarious, oneiric and fictional remembering

18825267 {18825267:7R9J5H9Z} 1 apa 50 default 6069 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%227R9J5H9Z%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Werning%20and%20Liefke%22%2C%22parsedDate%22%3A%222025-04-22%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BWerning%2C%20M.%2C%20%26amp%3B%20Liefke%2C%20K.%20%282025%29.%20Reference%20in%20memories%20from%20perceptual%20and%20non-perceptual%20experiences%3A%20a%20non-disjunctivist%20account%20including%20vicarious%2C%20oneiric%20and%20fictional%20remembering.%20%26lt%3Bi%26gt%3BSynthese%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B205%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%20186.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs11229-025-04936-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs11229-025-04936-5%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20in%20memories%20from%20perceptual%20and%20non-perceptual%20experiences%3A%20a%20non-disjunctivist%20account%20including%20vicarious%2C%20oneiric%20and%20fictional%20remembering%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Werning%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristina%22%2C%22lastName%22%3A%22Liefke%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20The%20paper%20argues%20for%20a%20non-disjunctivist%20account%20of%20reference%20in%20episodic%20memory.%20Our%20account%20provides%20a%20uniform%20theory%20of%20reference%20for%20episodic%20memories%20that%20root%20in%20veridical%20and%20non-veridical%20experiences.%20It%20is%20independent%20from%20the%20particular%20mechanisms%20that%20subserve%20the%20respective%20source%20experiences.%20We%20reject%20both%20relationalist%20and%20intentionalist%20analyses%20of%20memory%20and%20build%20our%20approach%20on%20Werning%20and%20Liefke%5Cu2019s%20theory%20of%20referential%20parasitism%20and%20Werning%5Cu2019s%20theory%20of%20trace%20minimalism.%20The%20motivation%20for%20our%20non-disjunctivist%20account%20is%20the%20assumption%20that%20perceptual%20and%20non-perceptual%20memories%20with%20an%20episodic%20character%20share%20a%20uniform%20underlying%20causal%20mechanism%20and%20thus%20make%20up%20one%20and%20the%20same%20natural%20kind.%22%2C%22date%22%3A%222025-04-22%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1007%5C%2Fs11229-025-04936-5%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flink.springer.com%5C%2F10.1007%5C%2Fs11229-025-04936-5%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221573-0964%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Werning, M., & Liefke, K. (2025). Reference in memories from perceptual and non-perceptual experiences: a non-disjunctivist account including vicarious, oneiric and fictional remembering. Synthese, 205(5), 186. https://doi.org/10.1007/s11229-025-04936-5

Posttraining noradrenergic stimulation maintains hippocampal engram reactivation and episodic-like specificity of remote memory

18825267 {18825267:GZF8K5K7} 1 apa 50 default 6059 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22GZF8K5K7%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Gulmez%20Karaca%20et%20al.%22%2C%22parsedDate%22%3A%222025-05-08%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BGulmez%20Karaca%2C%20K.%2C%20Bahtiyar%2C%20S.%2C%20Van%20Dongen%2C%20L.%2C%20Wolf%2C%20O.%20T.%2C%20Hermans%2C%20E.%20J.%2C%20Henckens%2C%20M.%20J.%20A.%20G.%2C%20%26amp%3B%20Roozendaal%2C%20B.%20%282025%29.%20Posttraining%20noradrenergic%20stimulation%20maintains%20hippocampal%20engram%20reactivation%20and%20episodic-like%20specificity%20of%20remote%20memory.%20%26lt%3Bi%26gt%3BNeuropsychopharmacology%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41386-025-02122-2%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41386-025-02122-2%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Posttraining%20noradrenergic%20stimulation%20maintains%20hippocampal%20engram%20reactivation%20and%20episodic-like%20specificity%20of%20remote%20memory%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kubra%22%2C%22lastName%22%3A%22Gulmez%20Karaca%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sevgi%22%2C%22lastName%22%3A%22Bahtiyar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Linde%22%2C%22lastName%22%3A%22Van%20Dongen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%20T.%22%2C%22lastName%22%3A%22Wolf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erno%20J.%22%2C%22lastName%22%3A%22Hermans%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marloes%20J.%20A.%20G.%22%2C%22lastName%22%3A%22Henckens%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benno%22%2C%22lastName%22%3A%22Roozendaal%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Recent%20findings%20indicate%20that%20noradrenergic%20arousal%20maintains%20long-term%20episodic-like%20specificity%20of%20memory.%20However%2C%20the%20neural%20mechanism%20of%20how%20norepinephrine%20can%20alter%20the%20temporal%20dynamics%20of%20systems%20consolidation%20to%20maintain%20hippocampus%20dependency%20of%20remote%20memory%20is%20currently%20unknown.%20Memories%20are%20stored%20within%20ensembles%20of%20neurons%20that%20become%20activated%20during%20learning%20and%20display%20strengthened%20mutual%20plasticity%20and%20connectivity.%20This%20strengthened%20connectivity%20is%20believed%20to%20guide%20the%20coordinated%20reactivation%20of%20these%20neurons%20upon%20subsequent%20memory%20recall.%20Here%2C%20we%20used%20male%20transgenic%20FosTRAP2xtdTomato%20mice%20to%20investigate%20whether%20the%20noradrenergic%20stimulant%20yohimbine%20administered%20systemically%20immediately%20after%20an%20episodic-like%20object-in-context%20training%20experience%20maintained%20long-term%20memory%20specificity%20which%20was%20joined%20by%20an%20enhanced%20reactivation%20of%20training-activated%20cells%20within%20the%20hippocampus%20during%20remote%20retention%20testing.%20We%20found%20that%20saline-treated%20control%20mice%20time-dependently%20lost%20their%20episodic-like%20specificity%20of%20memory%2C%20which%20was%20associated%20with%20a%20shift%20in%20neuronal%20reactivation%20from%20the%20dorsal%20hippocampus%20to%20the%20prelimbic%20cortex%20at%20a%2014-day%20retention%20test.%20Importantly%2C%20yohimbine-treated%20mice%20maintained%20episodic-like%20specificity%20of%20remote%20memory%20and%20retained%20high%20neuronal%20reactivation%20within%20the%20dorsal%20hippocampus%2C%20without%20a%20time-dependent%20increase%20in%20prelimbic%20cortex%20reactivation.%20These%20findings%20suggest%20that%20noradrenergic%20arousal%20shortly%20after%20training%20maintains%20episodic-like%20specificity%20of%20remote%20memory%20by%20strengthening%20the%20connectivity%20between%20training-activated%20hippocampal%20cells%20during%20consolidation%2C%20and%20provide%20a%20cellular%20model%20of%20how%20emotional%20memories%20remain%20vivid%20and%20detailed.%22%2C%22date%22%3A%222025-05-08%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41386-025-02122-2%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41386-025-02122-2%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220893-133X%2C%201740-634X%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A14Z%22%7D%7D%5D%7D
Gulmez Karaca, K., Bahtiyar, S., Van Dongen, L., Wolf, O. T., Hermans, E. J., Henckens, M. J. A. G., & Roozendaal, B. (2025). Posttraining noradrenergic stimulation maintains hippocampal engram reactivation and episodic-like specificity of remote memory. Neuropsychopharmacology. https://doi.org/10.1038/s41386-025-02122-2

Predictive processing’s flirt with transcendental idealism

18825267 {18825267:KSXIGS54} 1 apa 50 default 6055 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22KSXIGS54%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schlicht%22%2C%22parsedDate%22%3A%222025-05-15%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSchlicht%2C%20T.%20%282025%29.%20Predictive%20processing%26%23x2019%3Bs%20flirt%20with%20transcendental%20idealism.%20%26lt%3Bi%26gt%3BNo%26%23xFB%3Bs%26lt%3B%5C%2Fi%26gt%3B%2C%20nous.12552.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fnous.12552%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fnous.12552%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Predictive%20processing%27s%20flirt%20with%20transcendental%20idealism%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Schlicht%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20The%20popular%20predictive%20processing%20%28PP%29%20framework%20posits%20prediction%20error%20minimization%20%28PEM%29%20as%20the%20sole%20mechanism%20in%20the%20brain%20that%20can%20account%20for%20all%20mental%20phenomena%2C%20including%20consciousness.%20I%20first%20highlight%20three%20ambitions%20associated%20with%20major%20presentations%20of%20PP%3A%20%281%29%20Completeness%20%28PP%20aims%20for%20a%20comprehensive%20account%20of%20mental%20phenomena%29%2C%20%282%29%20Bayesian%20realism%20%28PP%20claims%20that%20PEM%20is%20implemented%20in%20the%20brain%20rather%20than%20providing%20only%20a%20model%29%2C%20and%20%283%29%20Naturalism%20%28PP%20is%20typically%20presented%20as%20yielding%20a%20naturalistic%20view%20of%20the%20mind%29.%20Then%20I%20demonstrate%20that%20many%20proponents%20of%20PP%20also%20endorse%20a%20form%20of%20Kantian%20transcendental%20idealism%20%28TI%29%2C%20based%20on%20a%20characterization%20of%20experiential%20content%20as%20the%20brain%26%23039%3Bs%20currently%20best%20hypothesis%20about%20the%20world.%20I%20argue%20that%20endorsing%20this%20claim%20%284%29%2C%20that%20is%2C%20that%20we%20only%20experience%20the%20world%20as%20it%20appears%2C%20but%20not%20the%20world%20itself%2C%20sabotages%20achieving%20the%20three%20ambitions.%20The%20argument%20proceeds%20by%20discussing%20the%20prospects%20of%20each%20ambition%20in%20turn%2C%20drawing%20on%20discussions%20in%20the%20philosophy%20of%20science%20about%20realism%20and%20its%20alternatives%2C%20about%20the%20motivation%20and%20features%20of%20computational%20models%2C%20and%20about%20the%20foundational%20role%20of%20consciousness%20for%20science.%22%2C%22date%22%3A%222025-05-15%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2Fnous.12552%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fnous.12552%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220029-4624%2C%201468-0068%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A14Z%22%7D%7D%5D%7D
Schlicht, T. (2025). Predictive processing’s flirt with transcendental idealism. Noûs, nous.12552. https://doi.org/10.1111/nous.12552

Remembering without (representational) memory: a neuro-computational study on regaining categoricity and compositionality from minimal traces

18825267 {18825267:C9JQJI7J} 1 apa 50 default 6039 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22C9JQJI7J%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fayyaz%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-22%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BFayyaz%2C%20Z.%2C%20Righetti%2C%20F.%2C%20Wiskott%2C%20L.%2C%20%26amp%3B%20Werning%2C%20M.%20%282025%29.%20Remembering%20without%20%28representational%29%20memory%3A%20a%20neuro-computational%20study%20on%20regaining%20categoricity%20and%20compositionality%20from%20minimal%20traces.%20%26lt%3Bi%26gt%3BPhilosophical%20Psychology%26lt%3B%5C%2Fi%26gt%3B%2C%201%26%23x2013%3B36.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09515089.2025.2522966%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09515089.2025.2522966%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Remembering%20without%20%28representational%29%20memory%3A%20a%20neuro-computational%20study%20on%20regaining%20categoricity%20and%20compositionality%20from%20minimal%20traces%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Zahra%22%2C%22lastName%22%3A%22Fayyaz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francesca%22%2C%22lastName%22%3A%22Righetti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laurenz%22%2C%22lastName%22%3A%22Wiskott%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Werning%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025-07-22%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1080%5C%2F09515089.2025.2522966%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.tandfonline.com%5C%2Fdoi%5C%2Ffull%5C%2F10.1080%5C%2F09515089.2025.2522966%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220951-5089%2C%201465-394X%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Fayyaz, Z., Righetti, F., Wiskott, L., & Werning, M. (2025). Remembering without (representational) memory: a neuro-computational study on regaining categoricity and compositionality from minimal traces. Philosophical Psychology, 1–36. https://doi.org/10.1080/09515089.2025.2522966

Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome

18825267 {18825267:4PDCX3FQ} 1 apa 50 default 6067 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%224PDCX3FQ%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Domschke%20et%20al.%22%2C%22parsedDate%22%3A%222025-04-25%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDomschke%2C%20K.%2C%20Schiele%2C%20M.%20A.%2C%20Crespo%20Salvador%2C%20%26%23xD3%3B.%2C%20Zillich%2C%20L.%2C%20Lipovsek%2C%20J.%2C%20Pittig%2C%20A.%2C%20Heinig%2C%20I.%2C%20Ridderbusch%2C%20I.%20C.%2C%20Straube%2C%20B.%2C%20Richter%2C%20J.%2C%20Hollandt%2C%20M.%2C%20Plag%2C%20J.%2C%20Fydrich%2C%20T.%2C%20Koelkebeck%2C%20K.%2C%20Weber%2C%20H.%2C%20Lueken%2C%20U.%2C%20Dannlowski%2C%20U.%2C%20Margraf%2C%20J.%2C%20Schneider%2C%20S.%2C%20%26%23x2026%3B%20Deckert%2C%20J.%20%282025%29.%20Epigenetic%20markers%20of%20disease%20risk%20and%20psychotherapy%20response%20in%20anxiety%20disorders%20%26%23x2013%3B%20a%20longitudinal%20analysis%20of%20the%20DNA%20methylome.%20%26lt%3Bi%26gt%3BMolecular%20Psychiatry%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41380-025-03038-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41380-025-03038-5%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Epigenetic%20markers%20of%20disease%20risk%20and%20psychotherapy%20response%20in%20anxiety%20disorders%20%5Cu2013%20a%20longitudinal%20analysis%20of%20the%20DNA%20methylome%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Domschke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Miriam%20A.%22%2C%22lastName%22%3A%22Schiele%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22%5Cu00d3scar%22%2C%22lastName%22%3A%22Crespo%20Salvador%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Zillich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan%22%2C%22lastName%22%3A%22Lipovsek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Pittig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ingmar%22%2C%22lastName%22%3A%22Heinig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabelle%20C.%22%2C%22lastName%22%3A%22Ridderbusch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%22%2C%22lastName%22%3A%22Straube%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maike%22%2C%22lastName%22%3A%22Hollandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%22%2C%22lastName%22%3A%22Plag%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Fydrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katja%22%2C%22lastName%22%3A%22Koelkebeck%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Heike%22%2C%22lastName%22%3A%22Weber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Lueken%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Udo%22%2C%22lastName%22%3A%22Dannlowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Margraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silvia%22%2C%22lastName%22%3A%22Schneider%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%20B.%22%2C%22lastName%22%3A%22Binder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Str%5Cu00f6hle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Winfried%22%2C%22lastName%22%3A%22Rief%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tilo%22%2C%22lastName%22%3A%22Kircher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Pauli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alfons%22%2C%22lastName%22%3A%22Hamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Volker%22%2C%22lastName%22%3A%22Arolt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Hoyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans-Ulrich%22%2C%22lastName%22%3A%22Wittchen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angelika%22%2C%22lastName%22%3A%22Erhardt-Lehmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22K%5Cu00f6ttgen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pascal%22%2C%22lastName%22%3A%22Schlosser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Deckert%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Epigenetic%20mechanisms%20such%20as%20DNA%20methylation%20are%20hypothesized%20to%20play%20a%20pivotal%20role%20in%20the%20pathogenesis%20of%20anxiety%20disorders%20and%20to%20predict%20as%20well%20as%20relate%20to%20treatment%20response.%20An%20epigenome-wide%20association%20study%20%28EWAS%29%20%28Illumina%20MethylationEPIC%20BeadChip%29%20was%20performed%20at%20baseline%20%28BL%29%2C%20post-treatment%20%28POST%29%20and%206-month%20follow-up%20%28FU%29%20in%20the%20so%20far%20largest%20longitudinal%20sample%20of%20patients%20with%20anxiety%20disorders%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009415%29%20treated%20with%20exposure-based%20cognitive%20behavioral%20therapy%20%28CBT%29%2C%20and%20in%20315%20healthy%20controls.%20Independent%20of%20comorbidity%20with%20depression%2C%20anxiety%20disorders%20were%20significantly%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%5Cu2264%5Cu20096.409E%5Cu201308%29%20associated%20with%20altered%20DNA%20methylation%20at%20148%20CpGs%20partly%20mapping%20to%20genes%20previously%20implicated%20in%20processes%20related%20to%20anxiety%2C%20brain%20disorders%2C%20learning%20or%20plasticity%20%28e.g.%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20GABBR2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20GABRD%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20GAST%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20IL12RB2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20LINC00293%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20LOC101928626%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20MFGE8%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20NOTCH4%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20PTPRN2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20RIMBP2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20SPTBN1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20or%20in%20a%20recent%20cross-anxiety%20disorders%20EWAS%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20TAOK1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20after%20pre-processing%20and%20quality%20control%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009378%20vs.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009295%29.%20Furthermore%2C%20BL%20DNA%20methylation%20at%20seven%20and%20three%20CpGs%2C%20respectively%2C%20was%20suggestively%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%26lt%3B%5Cu20091E%5Cu20135%29%20associated%20with%20treatment%20response%20at%20POST%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ABCA7%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ADRA2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20LTBR%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20RPSAP52%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20SH3RF3%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20SLC47A2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ZNF251%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20and%20FU%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ADGRD1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20PRSS58%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20USP47%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20Finally%2C%20suggestive%20evidence%20for%20dynamic%20epigenome-wide%20DNA%20methylation%20changes%20along%20with%20CBT%20response%20emerged%20at%20four%20CpGs%20from%20BL%20to%20FU%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ADIPOR2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20EIF3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20OCA2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20TMCC1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20The%20identification%20of%20epigenetic%20biomarkers%20may%20eventually%20aid%20in%20developing%20environment-based%20preventive%20strategies%20aimed%20at%20increasing%20resilience%20by%20providing%20deeper%20molecular%20insights%20into%20the%20mechanisms%20underlying%20anxiety%20disorders.%20Defining%20epigenetic%20signatures%20as%20predictors%20or%20key%20mechanisms%20in%20exposure-based%20interventions%20could%20pave%20the%20way%20for%20more%20targeted%20and%20personalized%20treatments%20for%20anxiety%20disorders.%22%2C%22date%22%3A%222025-04-25%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41380-025-03038-5%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41380-025-03038-5%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221359-4184%2C%201476-5578%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A05Z%22%7D%7D%5D%7D
Domschke, K., Schiele, M. A., Crespo Salvador, Ó., Zillich, L., Lipovsek, J., Pittig, A., Heinig, I., Ridderbusch, I. C., Straube, B., Richter, J., Hollandt, M., Plag, J., Fydrich, T., Koelkebeck, K., Weber, H., Lueken, U., Dannlowski, U., Margraf, J., Schneider, S., … Deckert, J. (2025). Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome. Molecular Psychiatry. https://doi.org/10.1038/s41380-025-03038-5

Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval

18825267 {18825267:M67AX4KF} 1 apa 50 default 6061 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22M67AX4KF%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Passiatore%20et%20al.%22%2C%22parsedDate%22%3A%222025-05-07%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPassiatore%2C%20R.%2C%20Lupo%2C%20A.%2C%20Sambuco%2C%20N.%2C%20Antonucci%2C%20L.%20A.%2C%20Stolfa%2C%20G.%2C%20Bertolino%2C%20A.%2C%20Popolizio%2C%20T.%2C%20Suchan%2C%20B.%2C%20%26amp%3B%20Pergola%2C%20G.%20%282025%29.%20Interindividual%20Variability%20in%20Memory%20Performance%20Is%20Related%20to%20Corticothalamic%20Networks%20during%20Memory%20Encoding%20and%20Retrieval.%20%26lt%3Bi%26gt%3BThe%20Journal%20of%20Neuroscience%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B45%26lt%3B%5C%2Fi%26gt%3B%2819%29%2C%20e0975242025.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1523%5C%2FJNEUROSCI.0975-24.2025%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1523%5C%2FJNEUROSCI.0975-24.2025%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Interindividual%20Variability%20in%20Memory%20Performance%20Is%20Related%20to%20Corticothalamic%20Networks%20during%20Memory%20Encoding%20and%20Retrieval%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roberta%22%2C%22lastName%22%3A%22Passiatore%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antonella%22%2C%22lastName%22%3A%22Lupo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicola%22%2C%22lastName%22%3A%22Sambuco%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Linda%20A.%22%2C%22lastName%22%3A%22Antonucci%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giuseppe%22%2C%22lastName%22%3A%22Stolfa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alessandro%22%2C%22lastName%22%3A%22Bertolino%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Teresa%22%2C%22lastName%22%3A%22Popolizio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Boris%22%2C%22lastName%22%3A%22Suchan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giulio%22%2C%22lastName%22%3A%22Pergola%22%7D%5D%2C%22abstractNote%22%3A%22Encoding%20new%20memories%20relies%20on%20functional%20connections%20between%20the%20medial%20temporal%20lobe%20and%20the%20frontoparietal%20cortices.%20Multiscan%20fMRI%20showed%20changes%20in%20these%20functional%20connections%20before%20and%20after%20memory%20encoding%2C%20potentially%20influenced%20by%20the%20thalamus.%20As%20different%20thalamic%20nuclei%20are%20interconnected%20with%20distinct%20cortical%20networks%2C%20we%20hypothesized%20that%20variations%20in%20corticothalamic%20recruitment%20may%20impact%20individual%20memory%20performance.%20We%20used%20a%20multiscan%20fMRI%20protocol%20including%20a%20resting-state%20scan%20followed%20by%20an%20associative%20memory%20task%20encompassing%20encoding%20and%20retrieval%20phases%2C%20in%20two%20independent%20samples%20of%20healthy%20adults%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%201%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu200929%2C%20mean%20age%5Cu2009%3D%5Cu200926%2C%20males%5Cu2009%3D%5Cu200935%25%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009108%2C%20mean%20age%5Cu2009%3D%5Cu200928%2C%20males%5Cu2009%3D%5Cu200952%25%29.%20Individual%20activity%20and%20functional%20connectivity%20were%20analyzed%20in%20the%20native%20space%20to%20minimize%20registration%20bias.%20By%20modeling%20the%20direct%20and%20indirect%20effects%20of%20corticothalamic%20recruitment%20on%20memory%20using%20structural%20equation%20modeling%2C%20we%20showed%20a%20positive%20association%20between%20resting-state%20functional%20connectivity%20of%20the%20medial%20thalamic%20subdivision%20within%20the%20frontoparietal%20network%20and%20memory%20performance%20across%20samples%20%28effect%20size%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20R%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ranging%20between%200.27%20and%200.36%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20-values%20between%200.01%20and%204%5Cu2009%5Cu00d7%5Cu200910%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu22125%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20This%20direct%20relationship%20was%20mediated%20by%20decreased%20activation%20of%20the%20anterior%20subdivision%20during%20encoding%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20R%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ranging%20between%200.04%20and%200.2%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20-values%20between%200.05%20and%200.006%29%20and%20by%20increased%20activation%20of%20the%20medial%20subdivision%20during%20retrieval%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20R%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ranging%20between%200.04%20and%200.2%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20-values%20between%200.05%20and%200.004%29.%20Moreover%2C%20three%20distinct%20clusters%20of%20individuals%20displayed%20different%20corticothalamic%20patterns%20across%20memory%20phases.%20We%20suggest%20that%20associative%20memory%20encoding%20relies%20on%20the%20distinct%20corticothalamic%20pathways%20involving%20medial%20thalamic%20recruitment%20and%20suppression%20of%20anterior%20subdivision%20to%20support%20the%20successful%20encoding%20of%20new%20memories.%22%2C%22date%22%3A%222025-05-07%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1523%5C%2FJNEUROSCI.0975-24.2025%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.jneurosci.org%5C%2Flookup%5C%2Fdoi%5C%2F10.1523%5C%2FJNEUROSCI.0975-24.2025%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220270-6474%2C%201529-2401%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A07Z%22%7D%7D%5D%7D
Passiatore, R., Lupo, A., Sambuco, N., Antonucci, L. A., Stolfa, G., Bertolino, A., Popolizio, T., Suchan, B., & Pergola, G. (2025). Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval. The Journal of Neuroscience, 45(19), e0975242025. https://doi.org/10.1523/JNEUROSCI.0975-24.2025

Representational dynamics during extinction of fear memories in the human brain

18825267 {18825267:XSMFRTA9} 1 apa 50 default 6650 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22XSMFRTA9%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Pacheco-Estefan%20et%20al.%22%2C%22parsedDate%22%3A%222025-08-05%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPacheco-Estefan%2C%20D.%2C%20Bouyeure%2C%20A.%2C%20Jacob%2C%20G.%2C%20Fellner%2C%20M.-C.%2C%20Lehongre%2C%20K.%2C%20Lambrecq%2C%20V.%2C%20Frazzini%2C%20V.%2C%20Navarro%2C%20V.%2C%20G%26%23xFC%3Bnt%26%23xFC%3Brk%26%23xFC%3Bn%2C%20O.%2C%20Shen%2C%20L.%2C%20Yang%2C%20J.%2C%20Han%2C%20B.%2C%20Chen%2C%20Q.%2C%20%26amp%3B%20Axmacher%2C%20N.%20%282025%29.%20Representational%20dynamics%20during%20extinction%20of%20fear%20memories%20in%20the%20human%20brain.%20%26lt%3Bi%26gt%3BNature%20Human%20Behaviour%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41562-025-02268-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41562-025-02268-5%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Representational%20dynamics%20during%20extinction%20of%20fear%20memories%20in%20the%20human%20brain%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Pacheco-Estefan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antoine%22%2C%22lastName%22%3A%22Bouyeure%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22George%22%2C%22lastName%22%3A%22Jacob%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie-Christin%22%2C%22lastName%22%3A%22Fellner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katia%22%2C%22lastName%22%3A%22Lehongre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Virginie%22%2C%22lastName%22%3A%22Lambrecq%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Valerio%22%2C%22lastName%22%3A%22Frazzini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%22%2C%22lastName%22%3A%22Navarro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Onur%22%2C%22lastName%22%3A%22G%5Cu00fcnt%5Cu00fcrk%5Cu00fcn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lu%22%2C%22lastName%22%3A%22Shen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jing%22%2C%22lastName%22%3A%22Yang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Biao%22%2C%22lastName%22%3A%22Han%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qi%22%2C%22lastName%22%3A%22Chen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nikolai%22%2C%22lastName%22%3A%22Axmacher%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Extinction%20learning%5Cu2014the%20suppression%20of%20a%20previously%20acquired%20fear%20response%5Cu2014is%20critical%20for%20adaptive%20behaviour%20and%20core%20for%20understanding%20the%20aetiology%20and%20treatment%20of%20anxiety%20disorders.%20Electrophysiological%20studies%20in%20rodents%20have%20revealed%20critical%20roles%20of%20theta%20%284%5Cu201312%5Cu2009Hz%29%20oscillations%20in%20amygdala%20and%20hippocampus%20during%20both%20fear%20learning%20and%20extinction%2C%20and%20engram%20research%20has%20shown%20that%20extinction%20relies%20on%20the%20formation%20of%20novel%2C%20highly%20context-dependent%20memory%20traces%20that%20suppress%20the%20initial%20fear%20memories.%20Whether%20similar%20processes%20occur%20in%20humans%20and%20how%20they%20relate%20to%20previously%20described%20neural%20mechanisms%20of%20episodic%20memory%20formation%20and%20retrieval%20remains%20unknown.%20Intracranial%20EEG%20recordings%20in%20epilepsy%20patients%20provide%20direct%20access%20to%20the%20deep%20brain%20structures%20of%20the%20fear%20and%20extinction%20network%2C%20while%20representational%20similarity%20analysis%20allows%20characterizing%20the%20memory%20traces%20of%20specific%20cues%20and%20contexts.%20Here%20we%20combined%20these%20methods%20to%20show%20that%20amygdala%20theta%20oscillations%20during%20extinction%20learning%20signal%20safety%20rather%20than%20threat%20and%20that%20extinction%20memory%20traces%20are%20characterized%20by%20stable%20and%20context-specific%20neural%20representations%20that%20are%20coordinated%20across%20the%20extinction%20network.%20We%20further%20demonstrate%20that%20context%20specificity%20during%20extinction%20learning%20predicts%20the%20reoccurrence%20of%20fear%20memory%20traces%20during%20a%20subsequent%20test%20period%2C%20while%20reoccurrence%20of%20extinction%20memory%20traces%20predicts%20safety%20responses.%20Our%20results%20reveal%20the%20neurophysiological%20mechanisms%20and%20representational%20characteristics%20of%20context-dependent%20extinction%20learning%20in%20the%20human%20brain.%20In%20addition%2C%20they%20show%20that%20the%20mutual%20competition%20of%20fear%20and%20extinction%20memory%20traces%20provides%20a%20mechanistic%20basis%20for%20clinically%20important%20phenomena%20such%20as%20fear%20renewal%20and%20extinction%20retrieval.%22%2C%22date%22%3A%222025-08-05%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41562-025-02268-5%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41562-025-02268-5%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%222397-3374%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Pacheco-Estefan, D., Bouyeure, A., Jacob, G., Fellner, M.-C., Lehongre, K., Lambrecq, V., Frazzini, V., Navarro, V., Güntürkün, O., Shen, L., Yang, J., Han, B., Chen, Q., & Axmacher, N. (2025). Representational dynamics during extinction of fear memories in the human brain. Nature Human Behaviour. https://doi.org/10.1038/s41562-025-02268-5

Out of touch? How trauma shapes the experience of social touch – neural and endocrine pathways

Scheele, 2024 Stevens L., Bregulla M., Scheele D. (2024). Out of touch? How trauma shapes the experience of social touch – neural and endocrine pathways. Neuroscience & Biobehavioral Reviews (in press)

Foundation Models – A New Paradigm for Artificial Intelligence

Meske, 2024 Schneider, J., Meske, C. and Kuss, P. (2024). Foundation Models – A New Paradigm for Artificial Intelligence. Business & Information Systems Engineering 66, 221–231. http://dx.doi.org/10.1007/s12599-024-00851-0

The value of mere completion

Hennecke, 2023 Converse, B. A., Tsang, S., & Hennecke, M. (2023). The value of mere completion. Journal of Experimental Psychology: General, 152(11), 3021–3036. https://doi.org/10.1037/xge0001434

Prediction error processing and sharpening of expected information across the face-processing hierarchy

Blank, 2024 Garlichs, A. & Blank, H. (2024). Prediction error processing and sharpening of expected information across the face-processing hierarchy. Nature Communications, 15, 3407.doi.org/10.1038/s41467-024-47749-9

Neural dynamic foundations of a theory of higher cognition: The case of grounding nested phrases.

Schöner & Sabinasz, 2023 Sabinasz, D., Richter, M., & Schöner, G. (2023). Neural dynamic foundations of a theory of higher cognition: The case of grounding nested phrases. Cognitive Neurodynamics.  https://doi.org/10.1007/s11571-023-10007-7

Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3

Cheng, 2023 de Jong, L. W., Nejad, M. M., Yoon, E., Cheng, S., & Diba, K. (2023). Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3. Current Biology. 33(9), 1689-1703.

Metacognition and self-control: An integrative framework. Psychological Review

Hennecke, 2023 Hennecke, M., & Bürgler, S.(2023). Metacognition and self-control: An integrative framework. Psychological Review, 130(5), 1262-1268. https://doi.org/10.1037/rev0000406

Mental Content

Schlicht, 2022 Dołęga, K., & Schlicht, T. (2022). Mental Content. In Mind, Cognition, and Neuroscience. Routledge.

Reflecting (on) Replica. Can We Have a Good Affective Relationship with a Social Chatbot?

Weber-Guskar, 2022 Weber-Guskar, E. (2022). Reflecting (on) Replica. Can We Have a Good Affective Relationship with a Social Chatbot? In: Social Robotics and the Good Life: The Normative Side of Forming Emotional Bonds With Robots. (2022). transcript Verlag....

Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution

Newen, 2023 Dung, L., & Newen, A. (2023). Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution. Cognition, 235, 105409. https://doi.org/10.1016/j.cognition.2023.105409

Avian navigation: Head direction cells in the quail hippocampus

Rose, 2021 Apostel, A., & Rose, J. (2021). Avian navigation: Head direction cells in the quail hippocampus. Current Biology, 31(12), R781–R783. https://doi.org/10.1016/j.cub.2021.04.071

A map of spatial navigation for neuroscience

Wiskott, 2023 Parra-Barrero, E., Vijayabaskaran, S., Seabrook, E., Wiskott, L., & Cheng, S. (2023). A map of spatial navigation for neuroscience. Neuroscience and biobehavioral reviews, 152, 105200. https://doi.org/10.1016/j.neubiorev.2023.105200

Mechanistic flexibility of the Retrosplenial Cortex enables its contribution to spatial cognition

Manahan-Vaughan, 2022 Stacho M, Manahan-Vaughan D (2022) Mechanistic flexibility of the Retrosplenial Cortex enables its contribution to spatial cognition. Trends Neurosci. 45:284- 296. doi: 10.1016/j.tins.2022.01.007

You can’t always get what you want: Predictive Processing and Consciousness.

Schlicht, 2021 Schlicht, T., Dolega, K. (2021) You can’t always get what you want: Predictive Processing and Consciousness. Philosophy and the Mind Scienceshttps://philosophymindscience.org/index.php/phimisci/article/view/9153

Suicide ideation during the COVID-19 outbreak in German university students: Comparison with pre-COVID 19 rates

Margraf, 2021 Brailovskaia, J., Teismann, T., Friedrich, S., Schneider, S., & Margraf, J. (2021). Suicide ideation during the COVID-19 outbreak in German university students: Comparison with pre-COVID 19 rates. Journal of Affective Disorders Reports, 6, 100228....

How to feel about emotionalized artificial intelligence? When robot pets, holograms, and chatbots become affective partners

Weber-Guskar, 2021 Weber-Guskar, E. (2021). How to feel about emotionalized artificial intelligence? When robot pets, holograms, and chatbots become affective partners. Ethics and Information Technology. https://doi.org/10.1007/s10676-021-09598-8

Retaliation or selfishness? An rTMS investigation of the role of the dorsolateral prefrontal cortex in prosocial motives

Brüne, 2018 Müller-Leinß, J.-M., Enzi, B., Flasbeck, V., & Brüne, M. (2018). Retaliation or selfishness? An rTMS investigation of the role of the dorsolateral prefrontal cortex in prosocial motives. Social Neuroscience, 13(6), 701–709....

Understanding another person’s emotions – an interdisciplinary research approach

Brüne, 2018 Juckel, G., Heinisch, C., Welpinghus, A., & Brüne, M. (2018). Understanding Another Person’s Emotions-An Interdisciplinary Research Approach. Frontiers in Psychiatry, 9, 414. https://doi.org/10.3389/fpsyt.2018.00414

A Perceptually Grounded Neural Dynamic Architecture Establishes Analogy Between Visual Object Pairs

Sabinasz & Schöner, 2022 Sabinasz, D. & Schöner, G. (2022). A Perceptually Grounded Neural Dynamic Architecture Establishes Analogy Between Visual Object Pairs. In J. Culbertson, Perfors, A., Rabagliati, H., & Ramenzoni, V. (Eds.), Proceedings of the 44th...

Berechenbare Gefühle? Grundlegendes zu einer Ethik der digitalen Emotionserfassung

Weber-Guskar, 2023 Weber-Guskar, E. (2023). Berechenbare Gefühle? Grundlegendes zu einer Ethik der digitalen Emotionserfassung. In: Schweiger, G., Zichy, M. (eds) Zwischenmenschliche Beziehungen im Zeitalter des Digitalen. Techno:Phil – Aktuelle Herausforderungen der...