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Relevant Publications
For full list of selected publications, see the publications page
Representational dynamics during extinction of fear memories in the human brain
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Pacheco-Estefan, D., Bouyeure, A., Jacob, G., Fellner, M.-C., Lehongre, K., Lambrecq, V., Frazzini, V., Navarro, V., Güntürkün, O., Shen, L., Yang, J., Han, B., Chen, Q., & Axmacher, N. (2025). Representational dynamics during extinction of fear memories in the human brain. Nature Human Behaviour. https://doi.org/10.1038/s41562-025-02268-5
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Pacheco-Estefan, D., Bouyeure, A., Jacob, G., Fellner, M.-C., Lehongre, K., Lambrecq, V., Frazzini, V., Navarro, V., Güntürkün, O., Shen, L., Yang, J., Han, B., Chen, Q., & Axmacher, N. (2025). Representational dynamics during extinction of fear memories in the human brain. Nature Human Behaviour. https://doi.org/10.1038/s41562-025-02268-5
Movie-watching evokes ripple-like activity within events and at event boundaries
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Domschke, K., Schiele, M. A., Crespo Salvador, Ó., Zillich, L., Lipovsek, J., Pittig, A., Heinig, I., Ridderbusch, I. C., Straube, B., Richter, J., Hollandt, M., Plag, J., Fydrich, T., Koelkebeck, K., Weber, H., Lueken, U., Dannlowski, U., Margraf, J., Schneider, S., … Deckert, J. (2025). Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome. Molecular Psychiatry. https://doi.org/10.1038/s41380-025-03038-5
Remembering without (representational) memory: a neuro-computational study on regaining categoricity and compositionality from minimal traces
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Fayyaz, Z., Righetti, F., Wiskott, L., & Werning, M. (2025). Remembering without (representational) memory: a neuro-computational study on regaining categoricity and compositionality from minimal traces. Philosophical Psychology, 1–36. https://doi.org/10.1080/09515089.2025.2522966
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The multidimensional profile methodology (MPM) for comparative cognition: towards a universal strategy of understanding animal minds
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Dung, L., & Newen, A. (2025). The multidimensional profile methodology (MPM) for comparative cognition: towards a universal strategy of understanding animal minds. Philosophical Studies. https://doi.org/10.1007/s11098-025-02363-3
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Schlicht, 2022 Schlicht, T. (2022). 1 Minds, Brains, and Deep Learning: The Development of Cognitive Science Through the Lens of Kant’s Approach to Cognition. Kant and Artificial Intelligence.
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Peters, Cosentino & Werning, 2022 Peeters, A., Cosentino, E., & Werning, M. (2022). Constructing a wider view on memory – Beyond the dichotomy of field and observer perspectives. In A. Berninger & Í. V. Ferran (eds.), Memory and Imagination (pp. 165–190)....
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Brüne, 2022 Engemann, L., Aweimer, A., Ewers, A., Afshari, F., Maiß, C., Kern, K., … & Brüne, M. (2022). Altered Left Ventricular Myocardial Deformation in Young Women With Borderline Personality Disorder: An Echocardiographic Study. Psychosomatic Medicine, 84(5),...
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Manahan-Vaughan, 2022 Strauch C., Angenstein F., Huong, T.H. & Manahan-Vaughan, D. (2022). Olfactory information encoding engages subcortical and cortical brain regions that enable sensory information processing and valence encoding. Cerebral Cortex 30(2)....
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Roelle, 2023 Roelle, J., Endres, T., Abel, R., Obergassel, N., Nückles, M., & Renkl, A. (2023). Happy together? On the relationship between research on retrieval practice and generative learning using the case of follow-up learning tasks. Educational Psychology...
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Schneider, 2022 Schoppmann, J., Schneider, S., & Seehagen, S. (2022). Can you teach me not to be angry? Relations between temperament and the emotion regulation strategy distraction in 2-year-olds. Child Development, 93(1), 165–179....
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Stacho & Manahan-Vaughan, 2022 Stacho M., & Manahan-Vaughan, D. (2022). Mechanistic flexibility of the Retrosplenial Cortex enables its contribution to spatial cognition. Trends In Neurosciences, 45(4), 284-296. https://doi.org/10.1016/j.tins.2022.01.007
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Weber-Guskar, 2022 Weber-Guskar, E. (2022). Reflecting (on) Replica. Can We Have a Good Affective Relationship with a Social Chatbot? In: Social Robotics and the Good Life: The Normative Side of Forming Emotional Bonds With Robots. (2022). transcript Verlag....
A map of spatial navigation for neuroscience
Wiskott, 2023 Parra-Barrero, E., Vijayabaskaran, S., Seabrook, E., Wiskott, L., & Cheng, S. (2023). A map of spatial navigation for neuroscience. Neuroscience and biobehavioral reviews, 152, 105200. https://doi.org/10.1016/j.neubiorev.2023.105200
Neural dynamic foundations of a theory of higher cognition: The case of grounding nested phrases.
Schöner & Sabinasz, 2023 Sabinasz, D., Richter, M., & Schöner, G. (2023). Neural dynamic foundations of a theory of higher cognition: The case of grounding nested phrases. Cognitive Neurodynamics. https://doi.org/10.1007/s11571-023-10007-7
The role of spontaneous recovery effects in the context of German orthography instruction methods with delayed correction.
Rummel, 2021 Erdmann, J., & Rummel, N. (2021). The role of spontaneous recovery effects in the context of German orthography instruction methods with delayed correction. Journal of Experimental Psychology Applied. https://doi.org/10.1037/xap0000377
How stress and glucocorticoids timing-dependently affect extinction and relapse
Wolf, 2018 Meir Drexler, S., Merz, C. J., Jentsch, V. L., & Wolf, O. T. (2018). How stress and glucocorticoids timing-dependently affect extinction and relapse. Neuroscience and Biobehavioral Reviews, 98, 145–153....
Higher functional connectivity between prefrontal regions and the dorsal attention network predicts absence of renewal.
Tegenthoff, 2021 Lissek, S., & Tegenthoff, M. (2021). Higher functional connectivity between prefrontal regions and the dorsal attention network predicts absence of renewal. Behavioural Brain Research, 412, 113413. https://doi.org/10.1016/j.bbr.2021.113413
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Horvath, 2022 Horvath, J., & Wiegmann, A. (2022). Intuitive Expertise in Moral Judgments. Australasian Journal of Philosophy, 100(2), 342–359. https://doi.org/10.1080/00048402.2021.1890162
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Werning, 2017 Werning, M., & Cosentino, E. (2017). The interaction of Bayesian pragmatics and lexical semantics in linguistic interpretation: Using event-related potentials to investigate hearers’ probabilistic predictions. In: G. Gunzelmann, A. Howes, T....
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Rummel, 2023 Brand, C., Hartmann, C., Loibl, K. & Rummel, N.v(2023). Do students learn more from failing alone or in groups? Insights into the effects of collaborative versus individual problem solving in productive failure. Instructional Science....
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Stacho & Manahan-Vaughan, 2022 Stacho M., & Manahan-Vaughan, D. (2022). Mechanistic flexibility of the Retrosplenial Cortex enables its contribution to spatial cognition. Trends In Neurosciences, 45(4), 284-296. https://doi.org/10.1016/j.tins.2022.01.007
Evidence for single-type semantics: An alternative to e/t-based dual-type semantics
Werning, 2018 Liefke, K., & Werning, M. (2018). Evidence for Single-Type Semantics—An Alternative To e/t-based Dual-Type Semantics. Journal of Semantics, 77, 107. https://doi.org/10.1093/jos/ffy009
Mental Content
Schlicht, 2022 Dołęga, K., & Schlicht, T. (2022). Mental Content. In Mind, Cognition, and Neuroscience. Routledge.
