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Relevant Publications
For full list of selected publications, see the publications page
Predictive processing’s flirt with transcendental idealism
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Schlicht, T. (2025). Predictive processing’s flirt with transcendental idealism. Noûs, nous.12552. https://doi.org/10.1111/nous.12552
Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval
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Passiatore, R., Lupo, A., Sambuco, N., Antonucci, L. A., Stolfa, G., Bertolino, A., Popolizio, T., Suchan, B., & Pergola, G. (2025). Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval. The Journal of Neuroscience, 45(19), e0975242025. https://doi.org/10.1523/JNEUROSCI.0975-24.2025
Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome
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Domschke, K., Schiele, M. A., Crespo Salvador, Ó., Zillich, L., Lipovsek, J., Pittig, A., Heinig, I., Ridderbusch, I. C., Straube, B., Richter, J., Hollandt, M., Plag, J., Fydrich, T., Koelkebeck, K., Weber, H., Lueken, U., Dannlowski, U., Margraf, J., Schneider, S., … Deckert, J. (2025). Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome. Molecular Psychiatry. https://doi.org/10.1038/s41380-025-03038-5
Movie-watching evokes ripple-like activity within events and at event boundaries
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Silva, M., Wu, X., Sabio, M., Conde-Blanco, E., Roldán, P., Donaire, A., Carreño, M., Axmacher, N., Baldassano, C., & Fuentemilla, L. (2025). Movie-watching evokes ripple-like activity within events and at event boundaries. Nature Communications, 16(1), 5647. https://doi.org/10.1038/s41467-025-60788-0
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Justin, M., Šešelja, D., Straßer, C., & Trpin, B. (2025). The Mix Matters: Exploring the Interplay Between Epistemic and Zetetic Norms in Scientific Disagreement. The British Journal for the Philosophy of Science, 737742. https://doi.org/10.1086/737742
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Lissek, S., & Tegenthoff, M. (2025). Regional prefrontal and hippocampal differences in gray matter volume are linked to the propensity for renewal in extinction learning. Frontiers in Behavioral Neuroscience, 19, 1592929. https://doi.org/10.3389/fnbeh.2025.1592929
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Teismann, T., Friedrich, S., & Margraf, J. (2025). Positive mental health predicts amelioration of suicidal ideation in patients undergoing cognitive behavioral therapy. Frontiers in Psychiatry, 16, 1571300. https://doi.org/10.3389/fpsyt.2025.1571300
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Labrenz, F., Kalenbach, A., Elsenbruch, S., & Icenhour, A. (2025). Costly pain avoidance and its impact on the modulation and extinction of visceral pain-related fear. Scientific Reports, 15(1), 27001. https://doi.org/10.1038/s41598-025-10499-9
Representational dynamics during extinction of fear memories in the human brain
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Pacheco-Estefan, D., Bouyeure, A., Jacob, G., Fellner, M.-C., Lehongre, K., Lambrecq, V., Frazzini, V., Navarro, V., Güntürkün, O., Shen, L., Yang, J., Han, B., Chen, Q., & Axmacher, N. (2025). Representational dynamics during extinction of fear memories in the human brain. Nature Human Behaviour. https://doi.org/10.1038/s41562-025-02268-5
Verlangsamung und Stillstand: Über eine Störung des Zeitbewusstseins und ihre ethische Relevanz
Weber-Guskar, 2023 Weber-Guskar, E. (2023). Verlangsamung und Stillstand: Über eine Störung des Zeitbewusstseins und ihre ethische Relevanz. Zeitschrift für Praktische Philosophie, 10(1). https://doi.org/10.22613/zfpp/10.1.9
Prediction error processing and sharpening of expected information across the face-processing hierarchy
Blank, 2024 Garlichs, A. & Blank, H. (2024). Prediction error processing and sharpening of expected information across the face-processing hierarchy. Nature Communications, 15, 3407.doi.org/10.1038/s41467-024-47749-9
The stabilization of visibility for sequentially presented, low-contrast objects: Experiments and neural field model.
Schöner, 2023 Hock, H. S., & Schöner, G. (2023). The stabilization of visibility for sequentially presented, low-contrast objects: Experiments and neural field model. Journal of Vision, 23(8), 12.https://doi.org/10.1167/jov.23.8.12
Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution.
Newen, 2023 Dung, L., & Newen, A. (2023). Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution. Cognition, 235, 105409. https://doi.org/10.1016/j.cognition.2023.105409
Berechenbare Gefühle? Grundlegendes zu einer Ethik der digitalen Emotionserfassung
Weber-Guskar, 2023 Weber-Guskar, E. (2023). Berechenbare Gefühle? Grundlegendes zu einer Ethik der digitalen Emotionserfassung. In: Schweiger, G., Zichy, M. (eds) Zwischenmenschliche Beziehungen im Zeitalter des Digitalen. Techno:Phil – Aktuelle Herausforderungen der...
The ALARM theory of consciousness: A two-level theory of phenomenal consciousness
Newen, 2023 Newen, A., & Montemayor, C. (2023). The ALARM theory of consciousness: A two-level theory of phenomenal consciousness. Journal of Consciousness Studies, 30(3-4), 84–105. https://doi.org/10.53765/20512201.30.3.084
Happy together? On the relationship between research on retrieval practice and generative learning using the case of follow-up learning tasks
Roelle, 2023 Roelle, J., Endres, T., Abel, R., Obergassel, N., Nückles, M., & Renkl, A. (2023). Happy together? On the relationship between research on retrieval practice and generative learning using the case of follow-up learning tasks. Educational Psychology...
Stress-Mediated Abnormalities in Regional Myocardial Wall Motion in Young Women with a History of Psychological Trauma
Brüne, 2023 Aweimer, A., Engemann, L., Amar, S., Ewers, A., Afshari, F., Maiß, C., Kern, K., Lücke, T., Mügge, A., El-Battrawy, I., Dietrich, J. W., & Brüne, M. (2023). Stress-Mediated Abnormalities in Regional Myocardial Wall Motion in Young Women with a History...
Olfactory information encoding engages subcortical and cortical brain regions that enable sensory information processing and valence encoding
Manahan-Vaughan, 2022 Strauch C., Angenstein F., Huong, T.H. & Manahan-Vaughan, D. (2022). Olfactory information encoding engages subcortical and cortical brain regions that enable sensory information processing and valence encoding. Cerebral Cortex 30(2)....
Deceptive XAI: Typology, Creation and Detection
Meske, 2024 Schneider, J., Meske, C. & Vlachos, M. (2024). Deceptive XAI: Typology, Creation and Detection. SN Computer Science 5, 81. https://doi.org/10.1007/s42979-023-02401-z
A methodological dilemma for investigating consciousness empirically
Schlicht, 2018 Schlicht, T. (2018). A methodological dilemma for investigating consciousness empirically. Consciousness and Cognition, 66, 91–100. https://doi.org/10.1016/j.concog.2018.11.002
When is learning “effortful”? Scrutinizing the concept of mental effort in cognitively-oriented research from a motivational perspective
Roelle, 2024 Grund, A., Fries, S., Nückles, M., Renkl, A., & Roelle, J. (2024). When is learning “effortful”? Scrutinizing the concept of mental effort in cognitively-oriented research from a motivational perspective. Educational Psychology Review, 36, Article...
Evidence for single-type semantics: An alternative to e/t-based dual-type semantics
Werning, 2018 Liefke, K., & Werning, M. (2018). Evidence for Single-Type Semantics—An Alternative To e/t-based Dual-Type Semantics. Journal of Semantics, 77, 107. https://doi.org/10.1093/jos/ffy009
Dynamical Systems Approaches to Cognition
Schöner, 2022 Schöner, G. (in press). Dynamical Systems Approaches to Cognition. In Sun, R (ed.), The Cambridge Handbook of Computational Psychology. 2nd Edition. Cambridge University Press.
Visual and Tactile Sensory Systems Share Common Features in Object Recognition.
Tegenthoff, 2021 Tabrik, S., Behroozi, M., Schlaffke, L., Heba, S., Lenz, M., Lissek, S., Güntürkün, O., Dinse, H. R., & Tegenthoff, M. (2021). Visual and Tactile Sensory Systems Share Common Features in Object Recognition. eNeuro, 8(5), ENEURO.0101-21.2021....
Do students learn more from failing alone or in groups? Insights into the effects of collaborative versus individual problem solving in productive failure
Rummel, 2023 Brand, C., Hartmann, C., Loibl, K. & Rummel, N.v(2023). Do students learn more from failing alone or in groups? Insights into the effects of collaborative versus individual problem solving in productive failure. Instructional Science....
Prediction error processing and sharpening of expected information across the face-processing hierarchy
Blank, 2024 Garlichs, A. & Blank, H. (2024). Prediction error processing and sharpening of expected information across the face-processing hierarchy. Nature Communications, 15, 3407.doi.org/10.1038/s41467-024-47749-9
A Model of Semantic Completion in Generative Episodic Memory
Wiskott, 2022 Fayyaz, Z., Altamimi, A., Zoellner, C., Klein, N., Wolf, O. T., Cheng, S., & Wiskott, L.. (2022). A Model of Semantic Completion in Generative Episodic Memory. Neural Computation, 34(9), 1841–1870. http://doi.org/10.1162/neco_a_01520
Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3
Cheng, 2023 de Jong, L. W., Nejad, M. M., Yoon, E., Cheng, S., & Diba, K. (2023). Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3. Current Biology. 33(9), 1689-1703.
Verlangsamung und Stillstand: Über eine Störung des Zeitbewusstseins und ihre ethische Relevanz
Weber-Guskar, 2023 Weber-Guskar, E. (2023). Verlangsamung und Stillstand: Über eine Störung des Zeitbewusstseins und ihre ethische Relevanz. Zeitschrift für Praktische Philosophie, 10(1). https://doi.org/10.22613/zfpp/10.1.9
