Recent News

Upcoming Events

01
Oct

<i>Cognitive Neuroscience</i> <br>Fourth Avian Cognitive Neuroscience Conference 2026<br><b>The bird's eye view on the evolution of cognition</b>

October 1
12:00 am - 11:59 pm
07
Oct

<i>Philosophy</i> <br>Alexander Klein (McMaster University & Betrand Russell Research Center) <br><b>Why Can't You See Your Own Eyes Move in a Mirror? E. B. Holt's Experimental Psychology as Pre-History of New Realism</b>

October 7
2:00 pm - 4:00 pm
21
Oct

<i>Philosophy</i> <br>Lukas Kob (Czech Academy of Sciences) <br><b>Holistic Representations in Large Language Models</b>

October 21
6:00 pm - 7:30 pm
22
Oct

Workshop:<br><b>Perception-Thought Transitions</b>

October 22
8:00 am - 5:00 pm
22
Oct

<i>Psychology</i> <br>Michael Levin (Tufts University) <br><b>How Cognition Emerges in Cell Collectives</b>

October 22
3:00 pm - 4:30 pm
28
Oct

<i>Philosophy</i> <br>Gualtiero Piccinini (University of Missouri) <br><b>Thought as an Inner Navigation: A Neurocognitive Architecture for Propositional Thought</b>

October 28
6:00 pm - 7:30 pm

Relevant Publications

For full list of selected publications, see the publications page

Positive mental health predicts amelioration of suicidal ideation in patients undergoing cognitive behavioral therapy

18825267 {18825267:XMMFN74Z} 1 apa 50 default 6041 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22XMMFN74Z%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Teismann%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-21%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTeismann%2C%20T.%2C%20Friedrich%2C%20S.%2C%20%26amp%3B%20Margraf%2C%20J.%20%282025%29.%20Positive%20mental%20health%20predicts%20amelioration%20of%20suicidal%20ideation%20in%20patients%20undergoing%20cognitive%20behavioral%20therapy.%20%26lt%3Bi%26gt%3BFrontiers%20in%20Psychiatry%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B16%26lt%3B%5C%2Fi%26gt%3B%2C%201571300.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffpsyt.2025.1571300%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffpsyt.2025.1571300%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Positive%20mental%20health%20predicts%20amelioration%20of%20suicidal%20ideation%20in%20patients%20undergoing%20cognitive%20behavioral%20therapy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Teismann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%5Cu00f6ren%22%2C%22lastName%22%3A%22Friedrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Margraf%22%7D%5D%2C%22abstractNote%22%3A%22Background%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Positive%20mental%20health%20has%20been%20shown%20to%20confer%20resilience%20against%20suicidal%20ideation%20and%20behavior.%20Yet%2C%20studies%20on%20treatment%20seeking%20populations%20are%20rare.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20The%20aim%20of%20the%20present%20study%20was%20to%20investigate%2C%20whether%20PMH%20predicts%20the%20amelioration%20of%20suicidal%20ideation%20in%20patients%20undergoing%20psychotherapy.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Method%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20Data%20from%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%3D%20959%20outpatients%20%2861.2%25%20female%3B%20age%3A%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20M%28SD%29%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%20%3D%2036.58%20%2813.29%29%2C%20range%3A%2018%5Cu201382%20years%29%2C%20who%20took%20part%20in%20a%20pretreatment%20and%20a%20posttreatment%20assessment%20after%2012%20sessions%20of%20cognitive%20behavioral%20therapy%2C%20were%20included.%20Self-report%20measures%20of%20positive%20mental%20health%2C%20depression%2C%20and%20suicidal%20ideation%5C%2Fbehavior%20were%20used.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Results%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Pretreatment%20PMH%20was%20shown%20to%20predict%20posttreatment%20suicidal%20ideation%20%5Cu2013%20after%20controlling%20for%20age%2C%20gender%2C%20pretreatment%20depression%2C%20suicidal%20ideation%20and%20lifetime%20suicide%20attempts.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Discussion%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Positive%20mental%20health%20might%20be%20understood%20as%20a%20protective%20factor%20in%20dealing%20with%20suicidal%20ideation.%20Findings%20underscore%20the%20need%20to%20focus%20on%20positive%20mental%20health%20in%20the%20risk-assessment%20and%20treatment%20of%20suicidal%20patients.%22%2C%22date%22%3A%222025-7-21%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.3389%5C%2Ffpsyt.2025.1571300%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.frontiersin.org%5C%2Farticles%5C%2F10.3389%5C%2Ffpsyt.2025.1571300%5C%2Ffull%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221664-0640%22%2C%22language%22%3A%22%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A14Z%22%7D%7D%5D%7D
Teismann, T., Friedrich, S., & Margraf, J. (2025). Positive mental health predicts amelioration of suicidal ideation in patients undergoing cognitive behavioral therapy. Frontiers in Psychiatry, 16, 1571300. https://doi.org/10.3389/fpsyt.2025.1571300

Prior knowledge activation as preparation prior to instruction: does the coverage of relevant prior knowledge affect learning?

18825267 {18825267:T9N28PEX} 1 apa 50 default 6043 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22T9N28PEX%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brand%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-11%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBrand%2C%20C.%2C%20Loibl%2C%20K.%2C%20%26amp%3B%20Rummel%2C%20N.%20%282025%29.%20Prior%20knowledge%20activation%20as%20preparation%20prior%20to%20instruction%3A%20does%20the%20coverage%20of%20relevant%20prior%20knowledge%20affect%20learning%3F%20%26lt%3Bi%26gt%3BInstructional%20Science%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs11251-025-09727-6%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs11251-025-09727-6%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Prior%20knowledge%20activation%20as%20preparation%20prior%20to%20instruction%3A%20does%20the%20coverage%20of%20relevant%20prior%20knowledge%20affect%20learning%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charleen%22%2C%22lastName%22%3A%22Brand%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Loibl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nikol%22%2C%22lastName%22%3A%22Rummel%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Two-phase%20instructional%20designs%20such%20as%20Productive%20and%20Vicarious%20Failure%20employ%20preparatory%20activities%20before%20explicit%20instruction.%20It%20is%20assumed%20that%20during%20this%20preparatory%20activity%2C%20students%20need%20to%20activate%20their%20prior%20knowledge%20in%20order%20to%20be%20prepared%20for%20subsequent%20instruction.%20However%2C%20empirical%20findings%20on%20this%20preparatory%20mechanism%20are%20scarce%2C%20and%20causal%20evidence%20is%20lacking.%20In%20an%20experimental%20design%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009165%29%2C%20we%20manipulated%20secondary%20school%20students%5Cu2019%20relevant%20prior%20knowledge%20activation%20by%20systematically%20varying%20the%20coverage%20of%20conceptual%20components%20of%20the%20targeted%20concept%20in%20solution%20attempts%20that%20students%20study%20in%20the%20preparatory%20phase%3A%20Students%20received%20solution%20attempts%20with%20either%20a%20high%20or%20a%20low%20coverage%20of%20conceptual%20components.%20The%20results%20reveal%20that%20students%20do%20not%20necessarily%20have%20to%20activate%20relevant%20prior%20knowledge%20covering%20all%20aspects%20of%20the%20targeted%20concept%20prior%20to%20instruction.%20Activating%20some%20relevant%20knowledge%20can%20prepare%20students%20for%20subsequent%20instruction%20and%20benefit%20students%20of%20all%20levels%20of%20prior%20knowledge.%20Moreover%2C%20we%20provide%20first%20evidence%20that%20students%5Cu2019%20prior%20knowledge%20activation%20becomes%20visible%20in%20their%20intermediate%20knowledge.%22%2C%22date%22%3A%222025-07-11%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1007%5C%2Fs11251-025-09727-6%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flink.springer.com%5C%2F10.1007%5C%2Fs11251-025-09727-6%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220020-4277%2C%201573-1952%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Brand, C., Loibl, K., & Rummel, N. (2025). Prior knowledge activation as preparation prior to instruction: does the coverage of relevant prior knowledge affect learning? Instructional Science. https://doi.org/10.1007/s11251-025-09727-6

Remembering without (representational) memory: a neuro-computational study on regaining categoricity and compositionality from minimal traces

18825267 {18825267:C9JQJI7J} 1 apa 50 default 6039 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22C9JQJI7J%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fayyaz%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-22%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BFayyaz%2C%20Z.%2C%20Righetti%2C%20F.%2C%20Wiskott%2C%20L.%2C%20%26amp%3B%20Werning%2C%20M.%20%282025%29.%20Remembering%20without%20%28representational%29%20memory%3A%20a%20neuro-computational%20study%20on%20regaining%20categoricity%20and%20compositionality%20from%20minimal%20traces.%20%26lt%3Bi%26gt%3BPhilosophical%20Psychology%26lt%3B%5C%2Fi%26gt%3B%2C%201%26%23x2013%3B36.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09515089.2025.2522966%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09515089.2025.2522966%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Remembering%20without%20%28representational%29%20memory%3A%20a%20neuro-computational%20study%20on%20regaining%20categoricity%20and%20compositionality%20from%20minimal%20traces%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Zahra%22%2C%22lastName%22%3A%22Fayyaz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francesca%22%2C%22lastName%22%3A%22Righetti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laurenz%22%2C%22lastName%22%3A%22Wiskott%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Werning%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025-07-22%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1080%5C%2F09515089.2025.2522966%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.tandfonline.com%5C%2Fdoi%5C%2Ffull%5C%2F10.1080%5C%2F09515089.2025.2522966%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220951-5089%2C%201465-394X%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Fayyaz, Z., Righetti, F., Wiskott, L., & Werning, M. (2025). Remembering without (representational) memory: a neuro-computational study on regaining categoricity and compositionality from minimal traces. Philosophical Psychology, 1–36. https://doi.org/10.1080/09515089.2025.2522966

Costly pain avoidance and its impact on the modulation and extinction of visceral pain-related fear

18825267 {18825267:MUNRQGPX} 1 apa 50 default 6037 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22MUNRQGPX%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Labrenz%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-24%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLabrenz%2C%20F.%2C%20Kalenbach%2C%20A.%2C%20Elsenbruch%2C%20S.%2C%20%26amp%3B%20Icenhour%2C%20A.%20%282025%29.%20Costly%20pain%20avoidance%20and%20its%20impact%20on%20the%20modulation%20and%20extinction%20of%20visceral%20pain-related%20fear.%20%26lt%3Bi%26gt%3BScientific%20Reports%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%2027001.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-025-10499-9%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-025-10499-9%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Costly%20pain%20avoidance%20and%20its%20impact%20on%20the%20modulation%20and%20extinction%20of%20visceral%20pain-related%20fear%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Labrenz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Kalenbach%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sigrid%22%2C%22lastName%22%3A%22Elsenbruch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adriane%22%2C%22lastName%22%3A%22Icenhour%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Along%20the%20gut-brain%20axis%2C%20visceral%20pain%20demonstrably%20evokes%20emotional%20learning%20and%20memory%20processes%20shaping%20behavior%20in%20clinically%20relevant%20ways.%20Avoidance%20motivated%20by%20learned%20fear%20may%20constitute%20a%20major%20obstacle%20to%20treatment%20success%20in%20extinction-based%20interventions.%20However%2C%20the%20effects%20of%20avoidance%20on%20visceral%20pain-related%20fear%20extinction%20remain%20poorly%20understood.%20By%20implementing%20an%20ecologically%20valid%20experimental%20protocol%2C%20we%20investigated%20how%20costly%20avoidance%20affects%20the%20modulation%20and%20extinction%20of%20visceral%20pain-related%20fear.%20Thirty-three%20healthy%20volunteers%20underwent%20conditioning%20with%20visual%20cues%20%28conditioned%20stimuli%3B%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2CCS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2212%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20consistently%20followed%20by%20visceral%20pain%20or%20remaining%20unpaired.%20During%20avoidance%2C%20participants%20decided%20to%20avoid%20or%20receive%20pain%20upon%20confronting%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20.%20Avoidance%20decisions%20resulted%20in%20pain%20omission%20in%20some%20trials%2C%20while%20in%20others%2C%20participants%20experienced%20unpredictable%20pain.%20During%20extinction%2C%20CS%20were%20presented%20unpaired.%20CS%20valence%2C%20fear%2C%20and%20trial-by-trial%20decisions%20were%20analyzed.%20Avoidance%20decisions%20depended%20on%20prior%20experiences%2C%20with%20the%20highest%20probability%20of%20avoidance%20following%20successful%20pain%20omission.%20Negative%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20valence%20and%20fear%20remained%20elevated%20across%20avoidance%20and%20extinction.%20Learned%20fear%20and%20more%20avoidance%20decisions%20explained%2057%25%20variance%20in%20sustained%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20fear.%20Our%20findings%20indicate%20that%20avoidance%2C%20which%20provides%20short-term%20absence%20of%20pain%20even%20when%20followed%20by%20unpredictable%20pain%2C%20motivates%20its%20maintenance.%20However%2C%20it%20perpetuates%20pain-related%20fear%20and%20may%20impede%20extinction%2C%20with%20implications%20for%20persisting%20symptoms%20and%20therapeutic%20outcomes%20in%20chronic%20visceral%20pain.%22%2C%22date%22%3A%222025-07-24%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41598-025-10499-9%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41598-025-10499-9%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%222045-2322%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A04Z%22%7D%7D%5D%7D
Labrenz, F., Kalenbach, A., Elsenbruch, S., & Icenhour, A. (2025). Costly pain avoidance and its impact on the modulation and extinction of visceral pain-related fear. Scientific Reports, 15(1), 27001. https://doi.org/10.1038/s41598-025-10499-9

Regional prefrontal and hippocampal differences in gray matter volume are linked to the propensity for renewal in extinction learning

18825267 {18825267:IKXUVIP3} 1 apa 50 default 6045 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22IKXUVIP3%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Lissek%20and%20Tegenthoff%22%2C%22parsedDate%22%3A%222025-07-03%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLissek%2C%20S.%2C%20%26amp%3B%20Tegenthoff%2C%20M.%20%282025%29.%20Regional%20prefrontal%20and%20hippocampal%20differences%20in%20gray%20matter%20volume%20are%20linked%20to%20the%20propensity%20for%20renewal%20in%20extinction%20learning.%20%26lt%3Bi%26gt%3BFrontiers%20in%20Behavioral%20Neuroscience%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B19%26lt%3B%5C%2Fi%26gt%3B%2C%201592929.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffnbeh.2025.1592929%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffnbeh.2025.1592929%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Regional%20prefrontal%20and%20hippocampal%20differences%20in%20gray%20matter%20volume%20are%20linked%20to%20the%20propensity%20for%20renewal%20in%20extinction%20learning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silke%22%2C%22lastName%22%3A%22Lissek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Tegenthoff%22%7D%5D%2C%22abstractNote%22%3A%22Introduction%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20The%20renewal%20effect%20of%20extinction%20describes%20the%20reoccurrence%20of%20an%20extinguished%20response%20if%20recall%20is%20performed%20in%20a%20context%20that%20is%20not%20the%20same%20as%20the%20extinction%20context.%20This%20learning%20phenomenon%20is%20clinically%20relevant%2C%20since%20it%20potentially%20interferes%20with%20therapy%20success%20for%20anxiety%20disorders%20or%20phobias.%20The%20propensity%20to%20show%20the%20renewal%20effect%20appears%20to%20be%20a%20stable%20processing%20strategy%20in%20context-related%20extinction%2C%20associated%20with%20higher%20BOLD%20activation%20in%20hippocampus%2C%20ventromedial%20PFC%20%28vmPFC%29%20and%20inferior%20frontal%20gyrus%20%28IFG%29%20in%20individuals%20who%20show%20renewal%20%28REN%29%20compared%20to%20those%20who%20do%20not%20%28NoREN%29.%20However%2C%20evidence%20on%20a%20potential%20relationship%20between%20structural%20properties%20such%20as%20gray%20matter%20volume%20%28GMV%29%20in%20these%20regions%20and%20the%20propensity%20to%20show%20renewal%20is%20lacking.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Methods%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20In%20this%20study%2C%20we%20applied%20voxel-based%20morphometry%20%28VBM%29%20to%20investigate%20whether%20individuals%20with%20and%20without%20a%20propensity%20for%20renewal%20differ%20regarding%20their%20GMV%20in%20extinction-related%20brain%20regions%2C%20and%20whether%20such%20a%20difference%20is%20linked%20to%20the%20renewal%20level.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Results%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Results%20revealed%20differential%20GMV%20in%20REN%20and%20NoREN%20in%20adjacent%20subregions%20of%20IFG%20and%20vmPFC%2C%20respectively.%20Higher%20GMV%20in%20REN%20was%20located%20predominantly%20in%20orbital%20IFG%20and%20in%20BA10%20of%20vmPFC.%20Higher%20GMV%20in%20NoREN%20was%20located%20predominantly%20in%20triangular%20IFG%20and%20in%20BA%2011%20of%20vmPFC.%20In%20bilateral%20anterior%20cingulate%20cortex%20%28ACC%29%20and%20anterior%20hippocampus%2C%20GMV%20was%20overall%20higher%20in%20NoREN.%20In%20the%20complete%20sample%2C%20higher%20GMV%20in%20IFG%20BA%2047%2C%20vmPFC%20BA11%2C%20bilateral%20ACC%20and%20bilateral%20anterior%20hippocampus%20was%20associated%20with%20less%20renewal%2C%20and%20partially%20with%20a%20higher%20error%20level%20in%20extinction%20learning%20in%20a%20novel%20context.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Discussion%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20The%20findings%20suggest%20that%20higher%20GMV%20in%20several%20regions%20active%20during%20extinction%20learning%20may%20support%20a%20more%20thorough%20processing%20of%20extinction%20trials%20which%20in%20turn%20could%20be%20conducive%20to%20an%20extinction%20recall%20solely%20based%20on%20recent%20extinction%20memory%2C%20disregarding%20context%20information.%20In%20summary%2C%20this%20study%20provides%20first-time%20evidence%20for%20a%20relationship%20of%20GMV%20in%20of%20extinction-%20and%20renewal-relevant%20brain%20regions%20with%20behavioral%20performance%20during%20extinction%20learning%20and%20the%20propensity%20to%20show%20the%20renewal%20effect.%22%2C%22date%22%3A%222025-7-3%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.3389%5C%2Ffnbeh.2025.1592929%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.frontiersin.org%5C%2Farticles%5C%2F10.3389%5C%2Ffnbeh.2025.1592929%5C%2Ffull%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221662-5153%22%2C%22language%22%3A%22%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Lissek, S., & Tegenthoff, M. (2025). Regional prefrontal and hippocampal differences in gray matter volume are linked to the propensity for renewal in extinction learning. Frontiers in Behavioral Neuroscience, 19, 1592929. https://doi.org/10.3389/fnbeh.2025.1592929

Posttraining noradrenergic stimulation maintains hippocampal engram reactivation and episodic-like specificity of remote memory

18825267 {18825267:GZF8K5K7} 1 apa 50 default 6059 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22GZF8K5K7%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Gulmez%20Karaca%20et%20al.%22%2C%22parsedDate%22%3A%222025-05-08%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BGulmez%20Karaca%2C%20K.%2C%20Bahtiyar%2C%20S.%2C%20Van%20Dongen%2C%20L.%2C%20Wolf%2C%20O.%20T.%2C%20Hermans%2C%20E.%20J.%2C%20Henckens%2C%20M.%20J.%20A.%20G.%2C%20%26amp%3B%20Roozendaal%2C%20B.%20%282025%29.%20Posttraining%20noradrenergic%20stimulation%20maintains%20hippocampal%20engram%20reactivation%20and%20episodic-like%20specificity%20of%20remote%20memory.%20%26lt%3Bi%26gt%3BNeuropsychopharmacology%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41386-025-02122-2%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41386-025-02122-2%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Posttraining%20noradrenergic%20stimulation%20maintains%20hippocampal%20engram%20reactivation%20and%20episodic-like%20specificity%20of%20remote%20memory%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kubra%22%2C%22lastName%22%3A%22Gulmez%20Karaca%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sevgi%22%2C%22lastName%22%3A%22Bahtiyar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Linde%22%2C%22lastName%22%3A%22Van%20Dongen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%20T.%22%2C%22lastName%22%3A%22Wolf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erno%20J.%22%2C%22lastName%22%3A%22Hermans%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marloes%20J.%20A.%20G.%22%2C%22lastName%22%3A%22Henckens%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benno%22%2C%22lastName%22%3A%22Roozendaal%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Recent%20findings%20indicate%20that%20noradrenergic%20arousal%20maintains%20long-term%20episodic-like%20specificity%20of%20memory.%20However%2C%20the%20neural%20mechanism%20of%20how%20norepinephrine%20can%20alter%20the%20temporal%20dynamics%20of%20systems%20consolidation%20to%20maintain%20hippocampus%20dependency%20of%20remote%20memory%20is%20currently%20unknown.%20Memories%20are%20stored%20within%20ensembles%20of%20neurons%20that%20become%20activated%20during%20learning%20and%20display%20strengthened%20mutual%20plasticity%20and%20connectivity.%20This%20strengthened%20connectivity%20is%20believed%20to%20guide%20the%20coordinated%20reactivation%20of%20these%20neurons%20upon%20subsequent%20memory%20recall.%20Here%2C%20we%20used%20male%20transgenic%20FosTRAP2xtdTomato%20mice%20to%20investigate%20whether%20the%20noradrenergic%20stimulant%20yohimbine%20administered%20systemically%20immediately%20after%20an%20episodic-like%20object-in-context%20training%20experience%20maintained%20long-term%20memory%20specificity%20which%20was%20joined%20by%20an%20enhanced%20reactivation%20of%20training-activated%20cells%20within%20the%20hippocampus%20during%20remote%20retention%20testing.%20We%20found%20that%20saline-treated%20control%20mice%20time-dependently%20lost%20their%20episodic-like%20specificity%20of%20memory%2C%20which%20was%20associated%20with%20a%20shift%20in%20neuronal%20reactivation%20from%20the%20dorsal%20hippocampus%20to%20the%20prelimbic%20cortex%20at%20a%2014-day%20retention%20test.%20Importantly%2C%20yohimbine-treated%20mice%20maintained%20episodic-like%20specificity%20of%20remote%20memory%20and%20retained%20high%20neuronal%20reactivation%20within%20the%20dorsal%20hippocampus%2C%20without%20a%20time-dependent%20increase%20in%20prelimbic%20cortex%20reactivation.%20These%20findings%20suggest%20that%20noradrenergic%20arousal%20shortly%20after%20training%20maintains%20episodic-like%20specificity%20of%20remote%20memory%20by%20strengthening%20the%20connectivity%20between%20training-activated%20hippocampal%20cells%20during%20consolidation%2C%20and%20provide%20a%20cellular%20model%20of%20how%20emotional%20memories%20remain%20vivid%20and%20detailed.%22%2C%22date%22%3A%222025-05-08%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41386-025-02122-2%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41386-025-02122-2%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220893-133X%2C%201740-634X%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A14Z%22%7D%7D%5D%7D
Gulmez Karaca, K., Bahtiyar, S., Van Dongen, L., Wolf, O. T., Hermans, E. J., Henckens, M. J. A. G., & Roozendaal, B. (2025). Posttraining noradrenergic stimulation maintains hippocampal engram reactivation and episodic-like specificity of remote memory. Neuropsychopharmacology. https://doi.org/10.1038/s41386-025-02122-2

Neurite density but not myelination of specific fiber tracts links polygenic scores to general intelligence

18825267 {18825267:HEZKSS8T} 1 apa 50 default 6047 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22HEZKSS8T%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Stammen%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BStammen%2C%20C.%2C%20Penate%2C%20J.%20S.%2C%20Metzen%2C%20D.%2C%20H%26%23xF6%3Bnscher%2C%20M.%20J.%2C%20Fraenz%2C%20C.%2C%20Schl%26%23xFC%3Bter%2C%20C.%2C%20G%26%23xFC%3Bnt%26%23xFC%3Brk%26%23xFC%3Bn%2C%20O.%2C%20Kumsta%2C%20R.%2C%20%26amp%3B%20Gen%26%23xE7%3B%2C%20E.%20%282025%29.%20Neurite%20density%20but%20not%20myelination%20of%20specific%20fiber%20tracts%20links%20polygenic%20scores%20to%20general%20intelligence.%20%26lt%3Bi%26gt%3BCerebral%20Cortex%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B35%26lt%3B%5C%2Fi%26gt%3B%287%29%2C%20bhaf199.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fcercor%5C%2Fbhaf199%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fcercor%5C%2Fbhaf199%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Neurite%20density%20but%20not%20myelination%20of%20specific%20fiber%20tracts%20links%20polygenic%20scores%20to%20general%20intelligence%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christina%22%2C%22lastName%22%3A%22Stammen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Javier%20Schneider%22%2C%22lastName%22%3A%22Penate%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dorothea%22%2C%22lastName%22%3A%22Metzen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maurice%20J%22%2C%22lastName%22%3A%22H%5Cu00f6nscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Fraenz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Schl%5Cu00fcter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Onur%22%2C%22lastName%22%3A%22G%5Cu00fcnt%5Cu00fcrk%5Cu00fcn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Kumsta%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erhan%22%2C%22lastName%22%3A%22Gen%5Cu00e7%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20White%20matter%20is%20fundamental%20for%20efficient%20information%20transfer%20and%20thus%20crucial%20for%20intelligence.%20Previous%20studies%20demonstrated%20associations%20between%20fractional%20anisotropy%20and%20intelligence%2C%20but%20it%20remains%20unclear%20whether%20this%20relation%20is%20due%20to%20greater%20axon%20density%2C%20parallel%2C%20homogenous%20fiber%20orientation%20distributions%2C%20or%20greater%20myelination%2C%20as%20all%20influence%20fractional%20anisotropy.%20Using%20neurite%20orientation%20dispersion%20and%20density%20imaging%20and%20myelin%20water%20fraction%20imaging%2C%20we%20analyzed%20the%20microstructural%20architecture%20of%20intelligence%20in%20500%20healthy%20young%20adults.%20We%20were%20also%20interested%20whether%20specific%20white%20matter%20indices%20mediate%20the%20pathway%20linking%20genetic%20disposition%20for%20intelligence%20to%20phenotype.%20For%20the%20first%20time%2C%20we%20conducted%20mediation%20analyses%20investigating%20whether%20neurite%20density%20index%2C%20orientation%20dispersion%20index%2C%20and%20myelin%20water%20fraction%20of%2064%20white%20matter%20tracts%20mediate%20the%20effects%20of%20polygenic%20scores%20for%20intelligence%20on%20general%20intelligence%20%28g%29.%20Our%20results%20showed%20that%20neurite%20density%20index%2C%20but%20not%20orientation%20dispersion%20index%20or%20myelin%20water%20fraction%20of%20white%20matter%20tracts%2C%20was%20significantly%20associated%20with%20g%20and%20that%20neurite%20density%20index%20of%20six%20fiber%20tracts%20mediated%20the%20relation%20between%20genetic%20variability%20and%20g.%20These%20findings%20are%20a%20crucial%20step%20toward%20decoding%20the%20neurogenetic%20underpinnings%20of%20general%20intelligence%2C%20as%20they%20identify%20that%20neurite%20density%20of%20specific%20fiber%20tracts%20relates%20polygenic%20variation%20to%20g%2C%20whereas%20orientation%20dispersion%20and%20myelination%20did%20not.%22%2C%22date%22%3A%222025-07-01%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fcercor%5C%2Fbhaf199%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facademic.oup.com%5C%2Fcercor%5C%2Farticle%5C%2Fdoi%5C%2F10.1093%5C%2Fcercor%5C%2Fbhaf199%5C%2F8216885%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221047-3211%2C%201460-2199%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A09Z%22%7D%7D%5D%7D
Stammen, C., Penate, J. S., Metzen, D., Hönscher, M. J., Fraenz, C., Schlüter, C., Güntürkün, O., Kumsta, R., & Genç, E. (2025). Neurite density but not myelination of specific fiber tracts links polygenic scores to general intelligence. Cerebral Cortex, 35(7), bhaf199. https://doi.org/10.1093/cercor/bhaf199

The multidimensional profile methodology (MPM) for comparative cognition: towards a universal strategy of understanding animal minds

18825267 {18825267:NUKXXC82} 1 apa 50 default 6051 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22NUKXXC82%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dung%20and%20Newen%22%2C%22parsedDate%22%3A%222025-06-24%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDung%2C%20L.%2C%20%26amp%3B%20Newen%2C%20A.%20%282025%29.%20The%20multidimensional%20profile%20methodology%20%28MPM%29%20for%20comparative%20cognition%3A%20towards%20a%20universal%20strategy%20of%20understanding%20animal%20minds.%20%26lt%3Bi%26gt%3BPhilosophical%20Studies%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs11098-025-02363-3%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs11098-025-02363-3%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20multidimensional%20profile%20methodology%20%28MPM%29%20for%20comparative%20cognition%3A%20towards%20a%20universal%20strategy%20of%20understanding%20animal%20minds%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leonard%22%2C%22lastName%22%3A%22Dung%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Albert%22%2C%22lastName%22%3A%22Newen%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20How%20can%20we%20develop%20an%20adequate%20scientific%20understanding%20of%20the%20minds%20of%20nonhuman%20animals%3F%20We%20argue%20for%20a%20methodology%20based%20on%20multi-dimensional%20profile%20accounts.%20Such%20accounts%20are%20already%20used%20for%20the%20comparative%20study%20of%20norm%20cognition%2C%20consciousness%2C%20empathy%20and%20causal%20cognition%2C%20among%20others.%20This%20methodology%20demands%20that%20a%20cognitive%20capacity%20is%20characterized%20by%20a%20set%20of%20independent%20dimensions%20where%20each%20dimension%20is%20connected%20to%20operationalizable%20empirical%20indicators.%20Based%20on%20the%20level%20of%20realization%20for%20each%20indicator%20the%20level%20of%20implementation%20of%20a%20dimension%20is%20determined%20for%20a%20species%2C%20resulting%20in%20a%20multi-dimensional%20profile%20for%20each%20species.%20We%20analyze%20what%20this%20methodology%20is%20committed%20to.%20Then%2C%20we%20argue%20that%20this%20methodology%20has%20several%20benefits%20over%20competing%20unidimensional%20methodologies%2C%20by%20overcoming%20intractable%20disagreements%2C%20capturing%20the%20evolutionary%20continuity%20of%20cognition%2C%20alleviating%20anthropocentrism%2C%20and%20delivering%20more%20informative%20accounts%20of%20animal%20cognition.%20By%20demonstrating%20how%20this%20multidimensional%20methodology%20can%20be%20fruitfully%20combined%20with%20a%20methodology%20which%20focuses%20on%20the%20search%20for%20natural%20kinds%20in%20comparative%20cognition%2C%20we%20address%20the%20most%20important%20objection%20to%20the%20multidimensional%20profile%20methodology.%20We%20conclude%20that%20multidimensional%20profile%20accounts%20of%20all%20complex%20cognitive%20capacities%20should%20be%20developed%20and%20then%20used%20to%20facilitate%20scientific%20understanding%20of%20animal%20minds.%22%2C%22date%22%3A%222025-06-24%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1007%5C%2Fs11098-025-02363-3%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flink.springer.com%5C%2F10.1007%5C%2Fs11098-025-02363-3%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220031-8116%2C%201573-0883%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A16Z%22%7D%7D%5D%7D
Dung, L., & Newen, A. (2025). The multidimensional profile methodology (MPM) for comparative cognition: towards a universal strategy of understanding animal minds. Philosophical Studies. https://doi.org/10.1007/s11098-025-02363-3

Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval

18825267 {18825267:M67AX4KF} 1 apa 50 default 6061 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22M67AX4KF%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Passiatore%20et%20al.%22%2C%22parsedDate%22%3A%222025-05-07%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPassiatore%2C%20R.%2C%20Lupo%2C%20A.%2C%20Sambuco%2C%20N.%2C%20Antonucci%2C%20L.%20A.%2C%20Stolfa%2C%20G.%2C%20Bertolino%2C%20A.%2C%20Popolizio%2C%20T.%2C%20Suchan%2C%20B.%2C%20%26amp%3B%20Pergola%2C%20G.%20%282025%29.%20Interindividual%20Variability%20in%20Memory%20Performance%20Is%20Related%20to%20Corticothalamic%20Networks%20during%20Memory%20Encoding%20and%20Retrieval.%20%26lt%3Bi%26gt%3BThe%20Journal%20of%20Neuroscience%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B45%26lt%3B%5C%2Fi%26gt%3B%2819%29%2C%20e0975242025.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1523%5C%2FJNEUROSCI.0975-24.2025%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1523%5C%2FJNEUROSCI.0975-24.2025%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Interindividual%20Variability%20in%20Memory%20Performance%20Is%20Related%20to%20Corticothalamic%20Networks%20during%20Memory%20Encoding%20and%20Retrieval%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roberta%22%2C%22lastName%22%3A%22Passiatore%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antonella%22%2C%22lastName%22%3A%22Lupo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicola%22%2C%22lastName%22%3A%22Sambuco%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Linda%20A.%22%2C%22lastName%22%3A%22Antonucci%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giuseppe%22%2C%22lastName%22%3A%22Stolfa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alessandro%22%2C%22lastName%22%3A%22Bertolino%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Teresa%22%2C%22lastName%22%3A%22Popolizio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Boris%22%2C%22lastName%22%3A%22Suchan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giulio%22%2C%22lastName%22%3A%22Pergola%22%7D%5D%2C%22abstractNote%22%3A%22Encoding%20new%20memories%20relies%20on%20functional%20connections%20between%20the%20medial%20temporal%20lobe%20and%20the%20frontoparietal%20cortices.%20Multiscan%20fMRI%20showed%20changes%20in%20these%20functional%20connections%20before%20and%20after%20memory%20encoding%2C%20potentially%20influenced%20by%20the%20thalamus.%20As%20different%20thalamic%20nuclei%20are%20interconnected%20with%20distinct%20cortical%20networks%2C%20we%20hypothesized%20that%20variations%20in%20corticothalamic%20recruitment%20may%20impact%20individual%20memory%20performance.%20We%20used%20a%20multiscan%20fMRI%20protocol%20including%20a%20resting-state%20scan%20followed%20by%20an%20associative%20memory%20task%20encompassing%20encoding%20and%20retrieval%20phases%2C%20in%20two%20independent%20samples%20of%20healthy%20adults%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%201%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu200929%2C%20mean%20age%5Cu2009%3D%5Cu200926%2C%20males%5Cu2009%3D%5Cu200935%25%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009108%2C%20mean%20age%5Cu2009%3D%5Cu200928%2C%20males%5Cu2009%3D%5Cu200952%25%29.%20Individual%20activity%20and%20functional%20connectivity%20were%20analyzed%20in%20the%20native%20space%20to%20minimize%20registration%20bias.%20By%20modeling%20the%20direct%20and%20indirect%20effects%20of%20corticothalamic%20recruitment%20on%20memory%20using%20structural%20equation%20modeling%2C%20we%20showed%20a%20positive%20association%20between%20resting-state%20functional%20connectivity%20of%20the%20medial%20thalamic%20subdivision%20within%20the%20frontoparietal%20network%20and%20memory%20performance%20across%20samples%20%28effect%20size%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20R%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ranging%20between%200.27%20and%200.36%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20-values%20between%200.01%20and%204%5Cu2009%5Cu00d7%5Cu200910%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu22125%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20This%20direct%20relationship%20was%20mediated%20by%20decreased%20activation%20of%20the%20anterior%20subdivision%20during%20encoding%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20R%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ranging%20between%200.04%20and%200.2%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20-values%20between%200.05%20and%200.006%29%20and%20by%20increased%20activation%20of%20the%20medial%20subdivision%20during%20retrieval%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20R%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%202%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ranging%20between%200.04%20and%200.2%3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20-values%20between%200.05%20and%200.004%29.%20Moreover%2C%20three%20distinct%20clusters%20of%20individuals%20displayed%20different%20corticothalamic%20patterns%20across%20memory%20phases.%20We%20suggest%20that%20associative%20memory%20encoding%20relies%20on%20the%20distinct%20corticothalamic%20pathways%20involving%20medial%20thalamic%20recruitment%20and%20suppression%20of%20anterior%20subdivision%20to%20support%20the%20successful%20encoding%20of%20new%20memories.%22%2C%22date%22%3A%222025-05-07%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1523%5C%2FJNEUROSCI.0975-24.2025%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.jneurosci.org%5C%2Flookup%5C%2Fdoi%5C%2F10.1523%5C%2FJNEUROSCI.0975-24.2025%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220270-6474%2C%201529-2401%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A07Z%22%7D%7D%5D%7D
Passiatore, R., Lupo, A., Sambuco, N., Antonucci, L. A., Stolfa, G., Bertolino, A., Popolizio, T., Suchan, B., & Pergola, G. (2025). Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval. The Journal of Neuroscience, 45(19), e0975242025. https://doi.org/10.1523/JNEUROSCI.0975-24.2025

Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome

18825267 {18825267:4PDCX3FQ} 1 apa 50 default 6067 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%224PDCX3FQ%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Domschke%20et%20al.%22%2C%22parsedDate%22%3A%222025-04-25%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDomschke%2C%20K.%2C%20Schiele%2C%20M.%20A.%2C%20Crespo%20Salvador%2C%20%26%23xD3%3B.%2C%20Zillich%2C%20L.%2C%20Lipovsek%2C%20J.%2C%20Pittig%2C%20A.%2C%20Heinig%2C%20I.%2C%20Ridderbusch%2C%20I.%20C.%2C%20Straube%2C%20B.%2C%20Richter%2C%20J.%2C%20Hollandt%2C%20M.%2C%20Plag%2C%20J.%2C%20Fydrich%2C%20T.%2C%20Koelkebeck%2C%20K.%2C%20Weber%2C%20H.%2C%20Lueken%2C%20U.%2C%20Dannlowski%2C%20U.%2C%20Margraf%2C%20J.%2C%20Schneider%2C%20S.%2C%20%26%23x2026%3B%20Deckert%2C%20J.%20%282025%29.%20Epigenetic%20markers%20of%20disease%20risk%20and%20psychotherapy%20response%20in%20anxiety%20disorders%20%26%23x2013%3B%20a%20longitudinal%20analysis%20of%20the%20DNA%20methylome.%20%26lt%3Bi%26gt%3BMolecular%20Psychiatry%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41380-025-03038-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41380-025-03038-5%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Epigenetic%20markers%20of%20disease%20risk%20and%20psychotherapy%20response%20in%20anxiety%20disorders%20%5Cu2013%20a%20longitudinal%20analysis%20of%20the%20DNA%20methylome%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Domschke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Miriam%20A.%22%2C%22lastName%22%3A%22Schiele%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22%5Cu00d3scar%22%2C%22lastName%22%3A%22Crespo%20Salvador%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Zillich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan%22%2C%22lastName%22%3A%22Lipovsek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Pittig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ingmar%22%2C%22lastName%22%3A%22Heinig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabelle%20C.%22%2C%22lastName%22%3A%22Ridderbusch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%22%2C%22lastName%22%3A%22Straube%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maike%22%2C%22lastName%22%3A%22Hollandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%22%2C%22lastName%22%3A%22Plag%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Fydrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katja%22%2C%22lastName%22%3A%22Koelkebeck%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Heike%22%2C%22lastName%22%3A%22Weber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Lueken%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Udo%22%2C%22lastName%22%3A%22Dannlowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Margraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silvia%22%2C%22lastName%22%3A%22Schneider%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%20B.%22%2C%22lastName%22%3A%22Binder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Str%5Cu00f6hle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Winfried%22%2C%22lastName%22%3A%22Rief%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tilo%22%2C%22lastName%22%3A%22Kircher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Pauli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alfons%22%2C%22lastName%22%3A%22Hamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Volker%22%2C%22lastName%22%3A%22Arolt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Hoyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans-Ulrich%22%2C%22lastName%22%3A%22Wittchen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angelika%22%2C%22lastName%22%3A%22Erhardt-Lehmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22K%5Cu00f6ttgen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pascal%22%2C%22lastName%22%3A%22Schlosser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Deckert%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Epigenetic%20mechanisms%20such%20as%20DNA%20methylation%20are%20hypothesized%20to%20play%20a%20pivotal%20role%20in%20the%20pathogenesis%20of%20anxiety%20disorders%20and%20to%20predict%20as%20well%20as%20relate%20to%20treatment%20response.%20An%20epigenome-wide%20association%20study%20%28EWAS%29%20%28Illumina%20MethylationEPIC%20BeadChip%29%20was%20performed%20at%20baseline%20%28BL%29%2C%20post-treatment%20%28POST%29%20and%206-month%20follow-up%20%28FU%29%20in%20the%20so%20far%20largest%20longitudinal%20sample%20of%20patients%20with%20anxiety%20disorders%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009415%29%20treated%20with%20exposure-based%20cognitive%20behavioral%20therapy%20%28CBT%29%2C%20and%20in%20315%20healthy%20controls.%20Independent%20of%20comorbidity%20with%20depression%2C%20anxiety%20disorders%20were%20significantly%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%5Cu2264%5Cu20096.409E%5Cu201308%29%20associated%20with%20altered%20DNA%20methylation%20at%20148%20CpGs%20partly%20mapping%20to%20genes%20previously%20implicated%20in%20processes%20related%20to%20anxiety%2C%20brain%20disorders%2C%20learning%20or%20plasticity%20%28e.g.%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20GABBR2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20GABRD%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20GAST%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20IL12RB2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20LINC00293%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20LOC101928626%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20MFGE8%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20NOTCH4%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20PTPRN2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20RIMBP2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20SPTBN1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20or%20in%20a%20recent%20cross-anxiety%20disorders%20EWAS%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20TAOK1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20after%20pre-processing%20and%20quality%20control%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009378%20vs.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20N%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%3D%5Cu2009295%29.%20Furthermore%2C%20BL%20DNA%20methylation%20at%20seven%20and%20three%20CpGs%2C%20respectively%2C%20was%20suggestively%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20p%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2009%26lt%3B%5Cu20091E%5Cu20135%29%20associated%20with%20treatment%20response%20at%20POST%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ABCA7%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ADRA2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20LTBR%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20RPSAP52%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20SH3RF3%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20SLC47A2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ZNF251%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20and%20FU%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ADGRD1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20PRSS58%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20USP47%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20Finally%2C%20suggestive%20evidence%20for%20dynamic%20epigenome-wide%20DNA%20methylation%20changes%20along%20with%20CBT%20response%20emerged%20at%20four%20CpGs%20from%20BL%20to%20FU%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20ADIPOR2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20EIF3B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20OCA2%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20TMCC1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20The%20identification%20of%20epigenetic%20biomarkers%20may%20eventually%20aid%20in%20developing%20environment-based%20preventive%20strategies%20aimed%20at%20increasing%20resilience%20by%20providing%20deeper%20molecular%20insights%20into%20the%20mechanisms%20underlying%20anxiety%20disorders.%20Defining%20epigenetic%20signatures%20as%20predictors%20or%20key%20mechanisms%20in%20exposure-based%20interventions%20could%20pave%20the%20way%20for%20more%20targeted%20and%20personalized%20treatments%20for%20anxiety%20disorders.%22%2C%22date%22%3A%222025-04-25%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41380-025-03038-5%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41380-025-03038-5%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221359-4184%2C%201476-5578%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A05Z%22%7D%7D%5D%7D
Domschke, K., Schiele, M. A., Crespo Salvador, Ó., Zillich, L., Lipovsek, J., Pittig, A., Heinig, I., Ridderbusch, I. C., Straube, B., Richter, J., Hollandt, M., Plag, J., Fydrich, T., Koelkebeck, K., Weber, H., Lueken, U., Dannlowski, U., Margraf, J., Schneider, S., … Deckert, J. (2025). Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome. Molecular Psychiatry. https://doi.org/10.1038/s41380-025-03038-5

Verlangsamung und Stillstand: Über eine Störung des Zeitbewusstseins und ihre ethische Relevanz

Weber-Guskar, 2023 Weber-Guskar, E. (2023). Verlangsamung und Stillstand: Über eine Störung des Zeitbewusstseins und ihre ethische Relevanz. Zeitschrift für Praktische Philosophie, 10(1). https://doi.org/10.22613/zfpp/10.1.9

The ALARM theory of consciousness: A two-level theory of phenomenal consciousness

Newen, 2023 Newen, A., & Montemayor, C. (2023). The ALARM theory of consciousness: A two-level theory of phenomenal consciousness. Journal of Consciousness Studies, 30(3-4), 84–105. https://doi.org/10.53765/20512201.30.3.084

Altered Left Ventricular Myocardial Deformation in Young Women With Borderline Personality Disorder: An Echocardiographic Study

Brüne, 2022 Engemann, L., Aweimer, A., Ewers, A., Afshari, F., Maiß, C., Kern, K., … & Brüne, M. (2022). Altered Left Ventricular Myocardial Deformation in Young Women With Borderline Personality Disorder: An Echocardiographic Study. Psychosomatic Medicine, 84(5),...

Out of touch? How trauma shapes the experience of social touch – neural and endocrine pathways

Scheele, 2024 Stevens L., Bregulla M., Scheele D. (2024). Out of touch? How trauma shapes the experience of social touch – neural and endocrine pathways. Neuroscience & Biobehavioral Reviews (in press)

Opposing serial effects of stimulus and choice in speech perception scale with context variability

Blank, 2024 Ufer, C. & Blank, H. (2024) Opposing serial effects of stimulus and choice in speech perception scale with context variability. iScience:110611.https://doi.org/10.1016/j.isci.2024.110611

Dynamical Systems Approaches to Cognition

Schöner, 2022 Schöner, G. (in press). Dynamical Systems Approaches to Cognition. In Sun, R (ed.), The Cambridge Handbook of Computational Psychology. 2nd Edition. Cambridge University Press.

Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution.

Newen, 2023 Dung, L., & Newen, A. (2023). Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution. Cognition, 235, 105409. https://doi.org/10.1016/j.cognition.2023.105409

Exploring accidental triggers of smart speakers

Kolossa, 2022 Schönherr, L., Golla, M., Eisenhofer, T., Wiele, J., Kolossa, D., & Holz, T. (2022). Exploring accidental triggers of smart speakers. Computer Speech & Language, 73, 101328. https://doi.org/10.1016/j.csl.2021.101328

Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution

Newen, 2023 Dung, L., & Newen, A. (2023). Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution. Cognition, 235, 105409. https://doi.org/10.1016/j.cognition.2023.105409

Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3

Cheng, 2023 de Jong, L. W., Nejad, M. M., Yoon, E., Cheng, S., & Diba, K. (2023). Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3. Current Biology. 33(9), 1689-1703.

Metacomprehension in Multiple Document Reading. Can Judgment Accuracy Be Fostered by Generating Twitter-Like Summaries?

Stadtler, 2023 Schuster, C., Alef, M., Mierwald, M., Brauch, N., & Stadtler, M. (2023). Metacomprehension in Multiple Document Reading. Can Judgment Accuracy Be Fostered by Generating Twitter-Like Summaries? Zeitschrift für Entwicklungspsychologie und Pädagogische...

Consequences of exposure to the thin ideal in mass media depend on moderators in young women: An experimental study.

Schneider, 2021 Munsch, S., Messerli-Bürgy, N., Meyer, A. H., Humbel, N., Schopf, K., Wyssen, A., Forrer, F., Biedert, E., Lennertz, J., Trier, S., Isenschmid, B., Milos, G., Claussen, M., Whinyates, K., Adolph, D., Margraf, J., Assion, H.-J., Teismann, T., Ueberberg,...

Minds, Brains, and Deep Learning: The Development of Cognitive Science Through the Lens of Kant’s Approach to Cognition

Schlicht, 2022 Schlicht, T. (2022). 1 Minds, Brains, and Deep Learning: The Development of Cognitive Science Through the Lens of Kant’s Approach to Cognition. Kant and Artificial Intelligence.

Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution.

Newen, 2023 Dung, L., & Newen, A. (2023). Profiles of animal consciousness: A species-sensitive, two-tier account to quality and distribution. Cognition, 235, 105409. https://doi.org/10.1016/j.cognition.2023.105409

Working memory capacity of crows and monkeys arises from similar neuronal computations

Rose, 2021 Hahn, L. A., Balakhonov, D., Fongaro, E., Nieder, A., & Rose, J. (2021). Working memory capacity of crows and monkeys arises from similar neuronal computations. eLife, 10, e72783. https://doi.org/10.7554/eLife.72783

Do students learn more from failing alone or in groups? Insights into the effects of collaborative versus individual problem solving in productive failure

Rummel, 2023 Brand, C., Hartmann, C., Loibl, K. & Rummel, N.v(2023). Do students learn more from failing alone or in groups? Insights into the effects of collaborative versus individual problem solving in productive failure. Instructional Science....

Factivity variation in episodic memory reports

Liefke & Werning, 2022 Liefke, K., & Werning, M. (in press). Factivity variation in episodic memory reports. In Y. Katsutoshi, T. Yasufumi, & K. Mineshima (Eds.), New Frontiers in Artificial Intelligence. Lecture Notes in Computer Science. Heidelberg:...

Doing without metarepresentation: Scenario construction explains the epistemic generativity and privileged status of episodic memory

Werning, 2018 Werning, M., & Cheng, S. (2018). Doing without metarepresentation: Scenario construction explains the epistemic generativity and privileged status of episodic memory. The Behavioral and Brain Sciences, 41, e34....

Philosophical analysis: the concept grounding view

Horvath, 2018 Horvath, J. (2018). Philosophical Analysis: The Concept Grounding View. Philosophy and Phenomenological Research, 97(3), 724–750. https://doi.org/10.1111/phpr.12378

The patterns of problematic social media use (SMU) and their relationship with online flow, life satisfaction, depression, anxiety and stress symptoms in Lithuania and in Germany

Margraf, 2021 Brailovskaia, J., Truskauskaite-Kuneviciene, I., Kazlauskas, E., & Margraf, J. (2021). The patterns of problematic social media use (SMU) and their relationship with online flow, life satisfaction, depression, anxiety and stress symptoms in Lithuania...