Recent News
Conference Homepage: https://predcommlab.github.io/symposium-2026/#about
Upcoming Events
21
Oct
<i>Philosophy</i> <br>Lukas Kob (Czech Academy of Sciences) <br><b>Holistic Representations in Large Language Models</b>
October 21
6:00 pm - 7:30 pm
22
Oct
Workshop:<br><b>Perception-Thought Transitions</b>
October 22
8:00 am - 5:00 pm
22
Oct
<i>Psychology</i> <br>Michael Levin (Tufts University) <br><b>How Cognition Emerges in Cell Collectives</b>
October 22
3:00 pm - 4:30 pm
26
Oct
<i>Biopsychology</i> <br>Merel Jager (RUB) <br><b>Reality, survivorship bias, smooth sailing & the paradox of individuality</b>
October 26
1:15 pm - 2:45 pm
27
Oct
<i>Psychology</i> <br>Katja Langer (RUB) <br><b>Accute stress effects on flexible emotion regulation choices: The moderation of working memory capacity </b>
October 27
4:15 pm - 5:45 pm
28
Oct
<i>Philosophy</i> <br>Gualtiero Piccinini (University of Missouri) <br><b>Thought as an Inner Navigation: A Neurocognitive Architecture for Propositional Thought</b>
October 28
6:00 pm - 7:30 pm
Relevant Publications
For full list of selected publications, see the publications page
With great(er) power comes great(er) responsibility: an intercultural investigation of the effect of social roles on moral responsibility attribution
Newen, 2025
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Willemsen, P., Newen, A., Prochownik, K., & Kaspar, K. (2025). With great(er) power comes great(er) responsibility: an intercultural investigation of the effect of social roles on moral responsibility attribution. Philosophical Psychology, 38(2), 820–846. https://doi.org/10.1080/09515089.2023.2213277
The Mix Matters: Exploring the Interplay Between Epistemic and Zetetic Norms in Scientific Disagreement
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Justin, M., Šešelja, D., Straßer, C., & Trpin, B. (2025). The Mix Matters: Exploring the Interplay Between Epistemic and Zetetic Norms in Scientific Disagreement. The British Journal for the Philosophy of Science, 737742. https://doi.org/10.1086/737742
Posttraining noradrenergic stimulation maintains hippocampal engram reactivation and episodic-like specificity of remote memory
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Gulmez Karaca, K., Bahtiyar, S., Van Dongen, L., Wolf, O. T., Hermans, E. J., Henckens, M. J. A. G., & Roozendaal, B. (2025). Posttraining noradrenergic stimulation maintains hippocampal engram reactivation and episodic-like specificity of remote memory. Neuropsychopharmacology. https://doi.org/10.1038/s41386-025-02122-2
Costly pain avoidance and its impact on the modulation and extinction of visceral pain-related fear
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Labrenz, F., Kalenbach, A., Elsenbruch, S., & Icenhour, A. (2025). Costly pain avoidance and its impact on the modulation and extinction of visceral pain-related fear. Scientific Reports, 15(1), 27001. https://doi.org/10.1038/s41598-025-10499-9
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Silva, M., Wu, X., Sabio, M., Conde-Blanco, E., Roldán, P., Donaire, A., Carreño, M., Axmacher, N., Baldassano, C., & Fuentemilla, L. (2025). Movie-watching evokes ripple-like activity within events and at event boundaries. Nature Communications, 16(1), 5647. https://doi.org/10.1038/s41467-025-60788-0
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Voelter, J., Postin, D., Croy, I., Hurlemann, R., & Scheele, D. (2025). A neural signature of touch aversion and interpersonal problems in Borderline Personality Disorder. Psychotherapy and Psychosomatics, 1–24. https://doi.org/10.1159/000545973
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Domschke, K., Schiele, M. A., Crespo Salvador, Ó., Zillich, L., Lipovsek, J., Pittig, A., Heinig, I., Ridderbusch, I. C., Straube, B., Richter, J., Hollandt, M., Plag, J., Fydrich, T., Koelkebeck, K., Weber, H., Lueken, U., Dannlowski, U., Margraf, J., Schneider, S., … Deckert, J. (2025). Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome. Molecular Psychiatry. https://doi.org/10.1038/s41380-025-03038-5
Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval
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https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
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Passiatore, R., Lupo, A., Sambuco, N., Antonucci, L. A., Stolfa, G., Bertolino, A., Popolizio, T., Suchan, B., & Pergola, G. (2025). Interindividual Variability in Memory Performance Is Related to Corticothalamic Networks during Memory Encoding and Retrieval. The Journal of Neuroscience, 45(19), e0975242025. https://doi.org/10.1523/JNEUROSCI.0975-24.2025
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Weber-Guskar, 2023 Weber-Guskar, E. (2023). Verlangsamung und Stillstand: Über eine Störung des Zeitbewusstseins und ihre ethische Relevanz. Zeitschrift für Praktische Philosophie, 10(1). https://doi.org/10.22613/zfpp/10.1.9
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Kolossa, 2022 Schönherr, L., Golla, M., Eisenhofer, T., Wiele, J., Kolossa, D., & Holz, T. (2022). Exploring accidental triggers of smart speakers. Computer Speech & Language, 73, 101328. https://doi.org/10.1016/j.csl.2021.101328
The value of mere completion
Hennecke, 2023 Converse, B. A., Tsang, S., & Hennecke, M. (2023). The value of mere completion. Journal of Experimental Psychology: General, 152(11), 3021–3036. https://doi.org/10.1037/xge0001434
The stabilization of visibility for sequentially presented, low-contrast objects: Experiments and neural field model.
Schöner, 2023 Hock, H. S., & Schöner, G. (2023). The stabilization of visibility for sequentially presented, low-contrast objects: Experiments and neural field model. Journal of Vision, 23(8), 12.https://doi.org/10.1167/jov.23.8.12
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Rummel, 2022 Van Leeuwen, A., & Rummel, N. (2022). The function of teacher dashboards depends on the amount of time pressure in the classroom situation: results from teacher interviews and an experimental study. Unterrichtswissenschaft, 50, 561–588....
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Cheng, 2023 de Jong, L. W., Nejad, M. M., Yoon, E., Cheng, S., & Diba, K. (2023). Optogenetics reveals paradoxical network stabilizations in hippocampal CA1 and CA3. Current Biology. 33(9), 1689-1703.
Prediction error processing and sharpening of expected information across the face-processing hierarchy
Blank, 2024 Garlichs, A. & Blank, H. (2024). Prediction error processing and sharpening of expected information across the face-processing hierarchy. Nature Communications, 15, 3407.doi.org/10.1038/s41467-024-47749-9
A conceptual framework for empathy in humans and nonhuman animals
Newen, 2023 Newen, A., Griem, M., Pika, S. (2023): A conceptual framework for empathy in humans and nonhuman animals. In: Wittgenstein and Beyond, Routledge, New York. DOI: 10.4324/9781003202929-15 Chapter PDF
Minds, Brains, and Deep Learning: The Development of Cognitive Science Through the Lens of Kant’s Approach to Cognition
Schlicht, 2022 Schlicht, T. (2022). 1 Minds, Brains, and Deep Learning: The Development of Cognitive Science Through the Lens of Kant’s Approach to Cognition. Kant and Artificial Intelligence.
When is learning “effortful”? Scrutinizing the concept of mental effort in cognitively-oriented research from a motivational perspective
Roelle, 2024 Grund, A., Fries, S., Nückles, M., Renkl, A., & Roelle, J. (2024). When is learning “effortful”? Scrutinizing the concept of mental effort in cognitively-oriented research from a motivational perspective. Educational Psychology Review, 36, Article...
Rethinking Integration of Epistemic Strategies in Social Understanding: Examining the Central Role of Mindreading in Pluralist Accounts
Newen, 2021 Wolf, J., Coninx, S., & Newen, A. (2021). Rethinking Integration of Epistemic Strategies in Social Understanding: Examining the Central Role of Mindreading in Pluralist Accounts. Erkenntnis. https://doi.org/10.1007/s10670-021-00486-7
How does an emotional culture of joy cultivate team resilience? A sociocognitive perspective
Weiss, 2021 Hartmann, S., Weiss, M., Hoegl, M., & Carmeli, A. (2021). How does an emotional culture of joy cultivate team resilience? A sociocognitive perspective. Journal of Organizational Behavior, 42(3), 313–331. https://doi.org/10.1002/job.2496
Designing for the co-Orchestration of Social Transitions between Individual, Small-Group and Whole-Class Learning in the Classroom.
Rummel, 2021 Olsen, J. K., Rummel, N., & Aleven, V. (2021). Designing for the co-Orchestration of Social Transitions between Individual, Small-Group and Whole-Class Learning in the Classroom. International Journal of Artificial Intelligence in Education, 31(1),...
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Wiskott, 2023 Parra-Barrero, E., Vijayabaskaran, S., Seabrook, E., Wiskott, L., & Cheng, S. (2023). A map of spatial navigation for neuroscience. Neuroscience and biobehavioral reviews, 152, 105200. https://doi.org/10.1016/j.neubiorev.2023.105200
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Schneider, 2021 Munsch, S., Messerli-Bürgy, N., Meyer, A. H., Humbel, N., Schopf, K., Wyssen, A., Forrer, F., Biedert, E., Lennertz, J., Trier, S., Isenschmid, B., Milos, G., Claussen, M., Whinyates, K., Adolph, D., Margraf, J., Assion, H.-J., Teismann, T., Ueberberg,...
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Newen, 2023 Newen, A., Griem, M., Pika, S. (2023): A conceptual framework for empathy in humans and nonhuman animals. In: Wittgenstein and Beyond, Routledge, New York. DOI: 10.4324/9781003202929-15 Chapter PDF
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Manahan-Vaughan, 2022 Strauch C., Angenstein F., Huong, T.H. & Manahan-Vaughan, D. (2022). Olfactory information encoding engages subcortical and cortical brain regions that enable sensory information processing and valence encoding. Cerebral Cortex 30(2)....
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Sabinasz & Schöner, 2022 Sabinasz, D. & Schöner, G. (2022). A Perceptually Grounded Neural Dynamic Architecture Establishes Analogy Between Visual Object Pairs. In J. Culbertson, Perfors, A., Rabagliati, H., & Ramenzoni, V. (Eds.), Proceedings of the 44th...
Constructing a wider view on memory – Beyond the dichotomy of field and observer perspectives
Peters, Cosentino & Werning, 2022 Peeters, A., Cosentino, E., & Werning, M. (2022). Constructing a wider view on memory – Beyond the dichotomy of field and observer perspectives. In A. Berninger & Í. V. Ferran (eds.), Memory and Imagination (pp. 165–190)....
Suicide ideation during the COVID-19 outbreak in German university students: Comparison with pre-COVID 19 rates
Margraf, 2021 Brailovskaia, J., Teismann, T., Friedrich, S., Schneider, S., & Margraf, J. (2021). Suicide ideation during the COVID-19 outbreak in German university students: Comparison with pre-COVID 19 rates. Journal of Affective Disorders Reports, 6, 100228....