Costly pain avoidance and its impact on the modulation and extinction of visceral pain-related fear

18825267 {18825267:MUNRQGPX} 1 apa 50 default 6037 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22MUNRQGPX%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Labrenz%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-24%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLabrenz%2C%20F.%2C%20Kalenbach%2C%20A.%2C%20Elsenbruch%2C%20S.%2C%20%26amp%3B%20Icenhour%2C%20A.%20%282025%29.%20Costly%20pain%20avoidance%20and%20its%20impact%20on%20the%20modulation%20and%20extinction%20of%20visceral%20pain-related%20fear.%20%26lt%3Bi%26gt%3BScientific%20Reports%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%2027001.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-025-10499-9%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-025-10499-9%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Costly%20pain%20avoidance%20and%20its%20impact%20on%20the%20modulation%20and%20extinction%20of%20visceral%20pain-related%20fear%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Labrenz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Kalenbach%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sigrid%22%2C%22lastName%22%3A%22Elsenbruch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adriane%22%2C%22lastName%22%3A%22Icenhour%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Along%20the%20gut-brain%20axis%2C%20visceral%20pain%20demonstrably%20evokes%20emotional%20learning%20and%20memory%20processes%20shaping%20behavior%20in%20clinically%20relevant%20ways.%20Avoidance%20motivated%20by%20learned%20fear%20may%20constitute%20a%20major%20obstacle%20to%20treatment%20success%20in%20extinction-based%20interventions.%20However%2C%20the%20effects%20of%20avoidance%20on%20visceral%20pain-related%20fear%20extinction%20remain%20poorly%20understood.%20By%20implementing%20an%20ecologically%20valid%20experimental%20protocol%2C%20we%20investigated%20how%20costly%20avoidance%20affects%20the%20modulation%20and%20extinction%20of%20visceral%20pain-related%20fear.%20Thirty-three%20healthy%20volunteers%20underwent%20conditioning%20with%20visual%20cues%20%28conditioned%20stimuli%3B%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2CCS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%5Cu2212%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%20consistently%20followed%20by%20visceral%20pain%20or%20remaining%20unpaired.%20During%20avoidance%2C%20participants%20decided%20to%20avoid%20or%20receive%20pain%20upon%20confronting%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20.%20Avoidance%20decisions%20resulted%20in%20pain%20omission%20in%20some%20trials%2C%20while%20in%20others%2C%20participants%20experienced%20unpredictable%20pain.%20During%20extinction%2C%20CS%20were%20presented%20unpaired.%20CS%20valence%2C%20fear%2C%20and%20trial-by-trial%20decisions%20were%20analyzed.%20Avoidance%20decisions%20depended%20on%20prior%20experiences%2C%20with%20the%20highest%20probability%20of%20avoidance%20following%20successful%20pain%20omission.%20Negative%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20valence%20and%20fear%20remained%20elevated%20across%20avoidance%20and%20extinction.%20Learned%20fear%20and%20more%20avoidance%20decisions%20explained%2057%25%20variance%20in%20sustained%20CS%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2B%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20fear.%20Our%20findings%20indicate%20that%20avoidance%2C%20which%20provides%20short-term%20absence%20of%20pain%20even%20when%20followed%20by%20unpredictable%20pain%2C%20motivates%20its%20maintenance.%20However%2C%20it%20perpetuates%20pain-related%20fear%20and%20may%20impede%20extinction%2C%20with%20implications%20for%20persisting%20symptoms%20and%20therapeutic%20outcomes%20in%20chronic%20visceral%20pain.%22%2C%22date%22%3A%222025-07-24%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41598-025-10499-9%22%2C%22ISSN%22%3A%222045-2322%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41598-025-10499-9%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A04Z%22%7D%7D%5D%7D
Labrenz, F., Kalenbach, A., Elsenbruch, S., & Icenhour, A. (2025). Costly pain avoidance and its impact on the modulation and extinction of visceral pain-related fear. Scientific Reports, 15(1), 27001. https://doi.org/10.1038/s41598-025-10499-9

The Mix Matters: Exploring the Interplay Between Epistemic and Zetetic Norms in Scientific Disagreement

18825267 {18825267:A9V66ZFI} 1 apa 50 default 6035 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22A9V66ZFI%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Justin%20et%20al.%22%2C%22parsedDate%22%3A%222025-07-24%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BJustin%2C%20M.%2C%20%26%23x160%3Be%26%23x161%3Belja%2C%20D.%2C%20Stra%26%23xDF%3Ber%2C%20C.%2C%20%26amp%3B%20Trpin%2C%20B.%20%282025%29.%20The%20Mix%20Matters%3A%20Exploring%20the%20Interplay%20Between%20Epistemic%20and%20Zetetic%20Norms%20in%20Scientific%20Disagreement.%20%26lt%3Bi%26gt%3BThe%20British%20Journal%20for%20the%20Philosophy%20of%20Science%26lt%3B%5C%2Fi%26gt%3B%2C%20737742.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1086%5C%2F737742%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1086%5C%2F737742%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Mix%20Matters%3A%20Exploring%20the%20Interplay%20Between%20Epistemic%20and%20Zetetic%20Norms%20in%20Scientific%20Disagreement%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Justin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dunja%22%2C%22lastName%22%3A%22%5Cu0160e%5Cu0161elja%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Stra%5Cu00dfer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Borut%22%2C%22lastName%22%3A%22Trpin%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025-07-24%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1086%5C%2F737742%22%2C%22ISSN%22%3A%220007-0882%2C%201464-3537%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.journals.uchicago.edu%5C%2Fdoi%5C%2F10.1086%5C%2F737742%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A16Z%22%7D%7D%5D%7D
Justin, M., Šešelja, D., Straßer, C., & Trpin, B. (2025). The Mix Matters: Exploring the Interplay Between Epistemic and Zetetic Norms in Scientific Disagreement. The British Journal for the Philosophy of Science, 737742. https://doi.org/10.1086/737742

Representational dynamics during extinction of fear memories in the human brain

18825267 {18825267:XSMFRTA9} 1 apa 50 default 6033 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22XSMFRTA9%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Pacheco-Estefan%20et%20al.%22%2C%22parsedDate%22%3A%222025-08-05%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPacheco-Estefan%2C%20D.%2C%20Bouyeure%2C%20A.%2C%20Jacob%2C%20G.%2C%20Fellner%2C%20M.-C.%2C%20Lehongre%2C%20K.%2C%20Lambrecq%2C%20V.%2C%20Frazzini%2C%20V.%2C%20Navarro%2C%20V.%2C%20G%26%23xFC%3Bnt%26%23xFC%3Brk%26%23xFC%3Bn%2C%20O.%2C%20Shen%2C%20L.%2C%20Yang%2C%20J.%2C%20Han%2C%20B.%2C%20Chen%2C%20Q.%2C%20%26amp%3B%20Axmacher%2C%20N.%20%282025%29.%20Representational%20dynamics%20during%20extinction%20of%20fear%20memories%20in%20the%20human%20brain.%20%26lt%3Bi%26gt%3BNature%20Human%20Behaviour%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41562-025-02268-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41562-025-02268-5%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Representational%20dynamics%20during%20extinction%20of%20fear%20memories%20in%20the%20human%20brain%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Pacheco-Estefan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antoine%22%2C%22lastName%22%3A%22Bouyeure%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22George%22%2C%22lastName%22%3A%22Jacob%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie-Christin%22%2C%22lastName%22%3A%22Fellner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katia%22%2C%22lastName%22%3A%22Lehongre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Virginie%22%2C%22lastName%22%3A%22Lambrecq%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Valerio%22%2C%22lastName%22%3A%22Frazzini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%22%2C%22lastName%22%3A%22Navarro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Onur%22%2C%22lastName%22%3A%22G%5Cu00fcnt%5Cu00fcrk%5Cu00fcn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lu%22%2C%22lastName%22%3A%22Shen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jing%22%2C%22lastName%22%3A%22Yang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Biao%22%2C%22lastName%22%3A%22Han%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qi%22%2C%22lastName%22%3A%22Chen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nikolai%22%2C%22lastName%22%3A%22Axmacher%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Extinction%20learning%5Cu2014the%20suppression%20of%20a%20previously%20acquired%20fear%20response%5Cu2014is%20critical%20for%20adaptive%20behaviour%20and%20core%20for%20understanding%20the%20aetiology%20and%20treatment%20of%20anxiety%20disorders.%20Electrophysiological%20studies%20in%20rodents%20have%20revealed%20critical%20roles%20of%20theta%20%284%5Cu201312%5Cu2009Hz%29%20oscillations%20in%20amygdala%20and%20hippocampus%20during%20both%20fear%20learning%20and%20extinction%2C%20and%20engram%20research%20has%20shown%20that%20extinction%20relies%20on%20the%20formation%20of%20novel%2C%20highly%20context-dependent%20memory%20traces%20that%20suppress%20the%20initial%20fear%20memories.%20Whether%20similar%20processes%20occur%20in%20humans%20and%20how%20they%20relate%20to%20previously%20described%20neural%20mechanisms%20of%20episodic%20memory%20formation%20and%20retrieval%20remains%20unknown.%20Intracranial%20EEG%20recordings%20in%20epilepsy%20patients%20provide%20direct%20access%20to%20the%20deep%20brain%20structures%20of%20the%20fear%20and%20extinction%20network%2C%20while%20representational%20similarity%20analysis%20allows%20characterizing%20the%20memory%20traces%20of%20specific%20cues%20and%20contexts.%20Here%20we%20combined%20these%20methods%20to%20show%20that%20amygdala%20theta%20oscillations%20during%20extinction%20learning%20signal%20safety%20rather%20than%20threat%20and%20that%20extinction%20memory%20traces%20are%20characterized%20by%20stable%20and%20context-specific%20neural%20representations%20that%20are%20coordinated%20across%20the%20extinction%20network.%20We%20further%20demonstrate%20that%20context%20specificity%20during%20extinction%20learning%20predicts%20the%20reoccurrence%20of%20fear%20memory%20traces%20during%20a%20subsequent%20test%20period%2C%20while%20reoccurrence%20of%20extinction%20memory%20traces%20predicts%20safety%20responses.%20Our%20results%20reveal%20the%20neurophysiological%20mechanisms%20and%20representational%20characteristics%20of%20context-dependent%20extinction%20learning%20in%20the%20human%20brain.%20In%20addition%2C%20they%20show%20that%20the%20mutual%20competition%20of%20fear%20and%20extinction%20memory%20traces%20provides%20a%20mechanistic%20basis%20for%20clinically%20important%20phenomena%20such%20as%20fear%20renewal%20and%20extinction%20retrieval.%22%2C%22date%22%3A%222025-08-05%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41562-025-02268-5%22%2C%22ISSN%22%3A%222397-3374%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41562-025-02268-5%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A15Z%22%7D%7D%5D%7D
Pacheco-Estefan, D., Bouyeure, A., Jacob, G., Fellner, M.-C., Lehongre, K., Lambrecq, V., Frazzini, V., Navarro, V., Güntürkün, O., Shen, L., Yang, J., Han, B., Chen, Q., & Axmacher, N. (2025). Representational dynamics during extinction of fear memories in the human brain. Nature Human Behaviour. https://doi.org/10.1038/s41562-025-02268-5

Neural correlates of human fear conditioning and sources of variability in 2199 individuals

18825267 {18825267:ZV3JXABC} 1 apa 50 default 6031 https://philosophy-cognition.com/cmc/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22ZV3JXABC%22%2C%22library%22%3A%7B%22id%22%3A18825267%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Radua%20et%20al.%22%2C%22parsedDate%22%3A%222025-08-23%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BRadua%2C%20J.%2C%20Savage%2C%20H.%20S.%2C%20Vilajosana%2C%20E.%2C%20Jamieson%2C%20A.%2C%20Abler%2C%20B.%2C%20%26%23xC5%3Bhs%2C%20F.%2C%20Beckers%2C%20T.%2C%20Cardoner%2C%20N.%2C%20Cisler%2C%20J.%20M.%2C%20Diniz%2C%20J.%20B.%2C%20Bach%2C%20D.%20R.%2C%20Elsenbruch%2C%20S.%2C%20Greening%2C%20S.%20G.%2C%20Holt%2C%20D.%20J.%2C%20Kaczkurkin%2C%20A.%20N.%2C%20Keil%2C%20A.%2C%20Kindt%2C%20M.%2C%20Koch%2C%20K.%2C%20LaBar%2C%20K.%20S.%2C%20%26%23x2026%3B%20Fullana%2C%20M.%20A.%20%282025%29.%20Neural%20correlates%20of%20human%20fear%20conditioning%20and%20sources%20of%20variability%20in%202199%20individuals.%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B16%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%207869.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-025-63078-x%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-025-63078-x%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Neural%20correlates%20of%20human%20fear%20conditioning%20and%20sources%20of%20variability%20in%202199%20individuals%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joaquim%22%2C%22lastName%22%3A%22Radua%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hannah%20S.%22%2C%22lastName%22%3A%22Savage%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Enric%22%2C%22lastName%22%3A%22Vilajosana%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alec%22%2C%22lastName%22%3A%22Jamieson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Birgit%22%2C%22lastName%22%3A%22Abler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fredrik%22%2C%22lastName%22%3A%22%5Cu00c5hs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tom%22%2C%22lastName%22%3A%22Beckers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Narc%5Cu00eds%22%2C%22lastName%22%3A%22Cardoner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Josh%20M.%22%2C%22lastName%22%3A%22Cisler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliana%20B.%22%2C%22lastName%22%3A%22Diniz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dominik%20R.%22%2C%22lastName%22%3A%22Bach%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sigrid%22%2C%22lastName%22%3A%22Elsenbruch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Steven%20G.%22%2C%22lastName%22%3A%22Greening%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daphne%20J.%22%2C%22lastName%22%3A%22Holt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antonia%20N.%22%2C%22lastName%22%3A%22Kaczkurkin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Keil%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Merel%22%2C%22lastName%22%3A%22Kindt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathrin%22%2C%22lastName%22%3A%22Koch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kevin%20S.%22%2C%22lastName%22%3A%22LaBar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlene%20L.%22%2C%22lastName%22%3A%22Lam%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%20L.%22%2C%22lastName%22%3A%22Larson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tina%20B.%22%2C%22lastName%22%3A%22Lonsdorf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%20J.%22%2C%22lastName%22%3A%22Merz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katie%20A.%22%2C%22lastName%22%3A%22McLaughlin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yuval%22%2C%22lastName%22%3A%22Neria%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20S.%22%2C%22lastName%22%3A%22Pine%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carien%20M.%22%2C%22lastName%22%3A%22Van%20Reekum%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%20J.%22%2C%22lastName%22%3A%22Shackman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carles%22%2C%22lastName%22%3A%22Soriano-Mas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Victor%20I.%22%2C%22lastName%22%3A%22Spoormaker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20M.%22%2C%22lastName%22%3A%22Stout%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%22%2C%22lastName%22%3A%22Straube%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Straube%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lauri%22%2C%22lastName%22%3A%22Tuominen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ren%5Cu00e9e%20M.%22%2C%22lastName%22%3A%22Visser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Ahumada%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Volker%22%2C%22lastName%22%3A%22Arolt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcelo%20C.%22%2C%22lastName%22%3A%22Batistuzzo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paulo%20R.%22%2C%22lastName%22%3A%22Baz%5Cu00e1n%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emma%20E.%22%2C%22lastName%22%3A%22Biggs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marta%22%2C%22lastName%22%3A%22Cano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pamela%22%2C%22lastName%22%3A%22Chavarr%5Cu00eda-Elizondo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Samuel%20E.%22%2C%22lastName%22%3A%22Cooper%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Udo%22%2C%22lastName%22%3A%22Dannlowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22V%5Cu00edctor%22%2C%22lastName%22%3A%22De%20La%20Pe%5Cu00f1a-Arteaga%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%20N.%22%2C%22lastName%22%3A%22DeCross%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Domschke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mana%20R.%22%2C%22lastName%22%3A%22Ehlers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%20L.%22%2C%22lastName%22%3A%22Graner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alfons%20O.%22%2C%22lastName%22%3A%22Hamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%20J.%22%2C%22lastName%22%3A%22Herrmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ashley%20A.%22%2C%22lastName%22%3A%22Huggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adriane%22%2C%22lastName%22%3A%22Icenhour%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Asier%22%2C%22lastName%22%3A%22Juaneda-Segu%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Junghoefer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tilo%22%2C%22lastName%22%3A%22Kircher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katja%22%2C%22lastName%22%3A%22Koelkebeck%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuel%22%2C%22lastName%22%3A%22Kuhn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Labrenz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shmuel%20M.%22%2C%22lastName%22%3A%22Lissek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Lotze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Lueken%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Margraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ignacio%22%2C%22lastName%22%3A%22Mart%5Cu00ednez-Zalaca%5Cu00edn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Moeck%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jayne%22%2C%22lastName%22%3A%22Morriss%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mar%5Cu00eda%22%2C%22lastName%22%3A%22Ortu%5Cu00f1o%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Pittig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Porta-Casteras%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabelle%20C.%22%2C%22lastName%22%3A%22Ridderbusch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Winfried%22%2C%22lastName%22%3A%22Rief%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kati%22%2C%22lastName%22%3A%22Roesmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00f6rgen%22%2C%22lastName%22%3A%22Ros%5Cu00e9n%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alena%20N.%22%2C%22lastName%22%3A%22Ru%5Cu00dfmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rachel%22%2C%22lastName%22%3A%22Sjouwerman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jennifer%22%2C%22lastName%22%3A%22Spohrs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Str%5Cu00f6hle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%22%2C%22lastName%22%3A%22Suarez-Jimenez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Ulrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans-Ulrich%22%2C%22lastName%22%3A%22Wittchen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xi%22%2C%22lastName%22%3A%22Zhu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Waller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henrik%22%2C%22lastName%22%3A%22Walter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%20M.%22%2C%22lastName%22%3A%22Thompson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janna%20Marie%22%2C%22lastName%22%3A%22Bas-Hoogendam%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nynke%20A.%22%2C%22lastName%22%3A%22Groenewold%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dan%22%2C%22lastName%22%3A%22J.%20Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nic%20J.%22%2C%22lastName%22%3A%22Van%20Der%20Wee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joseph%20E.%22%2C%22lastName%22%3A%22Dunsmoor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andre%20F.%22%2C%22lastName%22%3A%22Marquand%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ben%22%2C%22lastName%22%3A%22J.%20Harrison%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Miquel%20A.%22%2C%22lastName%22%3A%22Fullana%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025-08-23%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-025-63078-x%22%2C%22ISSN%22%3A%222041-1723%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41467-025-63078-x%22%2C%22collections%22%3A%5B%222ADRQ6UB%22%5D%2C%22dateModified%22%3A%222025-11-12T13%3A04%3A08Z%22%7D%7D%5D%7D
Radua, J., Savage, H. S., Vilajosana, E., Jamieson, A., Abler, B., Åhs, F., Beckers, T., Cardoner, N., Cisler, J. M., Diniz, J. B., Bach, D. R., Elsenbruch, S., Greening, S. G., Holt, D. J., Kaczkurkin, A. N., Keil, A., Kindt, M., Koch, K., LaBar, K. S., … Fullana, M. A. (2025). Neural correlates of human fear conditioning and sources of variability in 2199 individuals. Nature Communications, 16(1), 7869. https://doi.org/10.1038/s41467-025-63078-x
Award ceremony: Onur Güntürkün is Professor of the Year 2025

Award ceremony: Onur Güntürkün is Professor of the Year 2025

The biopsychologist at Ruhr University is not only considered an outstanding researcher. He is also very committed to his students. Prof. Dr. Dr. h. c. Onur Güntürkün from the Chair of Biopsychology at Ruhr University Bochum is Professor of the Year 2025. He was awarded the prize on October 27. The high-caliber jury, headed by Prof. Dr. Ulrich Radtke, honored Güntürkün for his “outstanding commitment as a university teacher and mentor.”

For the full article visit: RUB News